A second opinion on the need for new warnings on attention deficit hyperactivity disorder (ADHD) drugs from the FDA advisory committee contradicts The Pediatric Advisory Committee recommendation. More »

Research Review: Update on Child and Adolescent ADHD More »

New research into the genetic basis and possible genetic markers for attention-deficit/hyperactivity disorder may open the door for new treatments. There is a clear concordance between twins who have ADHD, as well as siblings. What can genetic mapping tell us about treating ADHD? More »

The disruption of dopamine transportation in brain white matter may be the underlying reason that children suffer from attention-deficit/hyperactivity disorder, or ADHD. In addition, MR diffusion tensor imaging suggests that drug therapy repairs the damaged fiber bundles indicated in ADHD pathology. More »

The past two decades have ushered in a new era of methodological advances in tools for noninvasive imaging of the living brain. The information gleaned from advances in neuroimaging have been used to provide insights into ADHD's etiology, diagnosis and treatment. More »

In the United States, approximately 2% to 6% of school-age children are diagnosed with attention-deficit/hyperactivity disorder. Despite more than 50 years of clinical and neuroscientific research, appropriate diagnostic and therapeutic interventions for ADHD are still an issue for many people, and although reports summarize the current knowledge, they use parameters that are still based on the same descriptive determinations that have plagued the field for years. More »

With all the various types of medications (e.g., stimulants, antidepressants, α-agonists and norepinephrine) as well as different formulations (e.g., once-daily/sustained-release versus regular formulations) that can be used to treat attention-deficit/hyperactivity disorder in adolescents, choosing the right one can be a difficult task. This analysis of the options will help make that choice easier. More »

Weight-based dosing strategies have been used in psychostimulant studies for ADHD in children between the ages of 6 and 12 years. The efficacy of weight-based psychostimulant doses changes throughout early childhood and into adolescence in ways that are not in keeping with weight-based dosing practices. Future treatment and research must explore new possibilities in order to afford patients the most benefit for the least amount of effective drug intervention. More »

Although ADHD can be effectively treated and can lead to significant dysfunction if left untreated, negative public perceptions still abound. Proper diagnosis, exploration of comorbid disorders and collaboration with other health care professionals may be the answer to ensuring positive outcomes for children afflicted with this disorder. More »

Over the past two decades, there has been considerable progress in understanding the functions of the prefrontal cortex of the brain and its regulation of mental activities that allow for self-control and goal-directed behaviors. These mental activities are unified under the term executive functions. More »