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Apathy and Its Treatment in Alzheimer's Disease and Other Dementias

By Paul F. Malloy, Ph.D., and Patricia A. Boyle, Ph.D. | November 1, 2005

Tekin S, Mega MS, Masterman DM et al. (2001), Orbitofrontal and anterior cingulate cortex neurofibrillary tangle burden is associated with agitation in Alzheimer disease. Ann Neurol 49(3):355-361.

Teri L (1997), Behavior and caregiver burden: behavioral problems in patients with Alzheimer disease and its association with caregiver distress. Alzheimer Dis Assoc Disord 11(suppl 4):S35-S38.

Teri L, Gallagher-Thompson D (1991), Cognitive-behavioral interventions for treatment of depression in Alzheimer's patients. Gerontologist 31(3):413-416.

Teri L, Gibbons LE, McCurry SM et al. (2003), Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial. JAMA 290(15):2015-2022 [see comments].

Teri L, Logsdon RG, Uomoto J, McCurry SM (1997), Behavioral treatment of depression in dementia patients: a controlled clinical trial. J Gerontol B Psychol Sci Soc Sci 52(4):P159-P166.

Trinh NH, Hoblyn J, Mohanty S, Yaffe K (2003), Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: a meta-analysis. JAMA 289(2):210-216 [see comments].

Wynn ZJ, Cummings JL (2004), Cholinesterase inhibitor therapies and neuropsychiatric manifestations of Alzheimer's disease. Dement Geriatr Cogn Disord 17(1-2):100-108.

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