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Clinical News & Knowledge: Alzheimer Disease and Dementia
PET radiotracer enters Alzheimer trial
Bayer Schering Pharma of Germany will provide its experimental PET radiotracer florbetaben to the Swiss-based biopharmaceutical company AC Immune to evaluate the effects of a vaccine being tested to treat patients with Alzheimer´s disease. More »
MRI software predicts Alzheimer's disease
Massachusetts General Hospital researchers are using automated MRI software to detect individuals in the preclinical phase of Alzheimer's disease with 95% accuracy. More »
MRI software accurately IDs preclinical Alzheimer’s disease
Massachusetts General Hospital researchers are using automated MRI software to detect individuals in the preclinical phase of Alzheimer’s disease with 95% accuracy, according to a cohort study. More »
Report from SNM: PET imaging of brain chemistry bolsters characterization of dementias
Imaging scientists achieved a major breakthrough when they proved it was possible to predict the onset of Alzheimer’s disease using PET scans of neurochemical activity. University of Michigan researchers are going for the next neuroimaging milestone by showing that the same technique can also aid in the differential diagnosis of dementia. More »
Mortality With Antipsychotic Use in Alzheimer Disease
Mortality in elderly patients with dementia markedly and progressively increases with extended use of antipsychotics, according to the first long-term controlled study of risk in this population. Earlier evidence of this risk was from short-term trials not exceeding 14 weeks. More »
Orthostatic Hypotension Increases the Risk of Alzheimer Disease
Alzheimer disease (AD) is more than twice as likely to develop in elderly persons with orthostatic hypotension (OH) as in those without OH, according to a new study presented at the Annual Meeting of the American Academy of Neurology. More »
Essential Tremor Increases Risk of Dementia
Elderly persons with essential tremor (ET) are almost twice as likely to have dementia as those without ET, according to a new study from Elan Louis, MD, professor of neurology, and colleagues at Columbia University in New York. More »
Comorbidity: Psychiatric Comorbidity in Persons With Dementia
The assessment and treatment of psychiatric symptoms in persons with cognitive dysfunction are becoming increasingly important. Prevalence estimates of dementia in the United States range from 5% in those aged 71 to 79 years to 25% to 50% in those 90 or older. More »
Volumetric MRI produces early warning on Alzheimer's disease
MRI measures of regional brain atrophy, taken at the University of California, San Diego, have established the basis for a new way to diagnose Alzheimer's disease. More »
Mortality With Antipsychotic Use in Alzheimer Disease
Mortality in elderly patients with dementia markedly and progressively increases with extended use of antipsychotics, according to the first long-term controlled study of risk in this population. Earlier evidence of this risk was from short-term trials not exceeding 14 weeks. More »
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