Vulvar vestibulitis syndrome (VVS) is thought to be the major cause of dyspareunia in pre-menopausal women. Current epidemiological estimates suggest a lifetime prevalence of approximately 10% for North American women (Harlow et al., 2001). Vulvar vestibulitis syndrome sufferers are often referred to mental health care professionals by gynecologists and other medical specialists who can find no organic basis for the pain and imply to the women that it is all in their heads. Mental health care professionals may make a variety of diagnoses and assumptions about the nature of the pain, ranging from poor sexual technique to somatization and then treat the women accordingly. These diagnoses and treatments rarely help, and women find themselves increasingly frustrated by an endless series of referrals and little pain relief. Moreover, there is much clinical evidence to suggest that the dyspareunia resulting from VVS has major deleterious effects on the quality of life and intimate relationships of young women (Binik et al., 2000).
"Julie" was a 25-year-old, unmarried law student who came to see me after finding my name on the Internet. She reported having consulted numerous medical professionals and several alternative medical specialists without any relief for her recurrent dyspareunia. Her psychosocial and sexual development were unremarkable, and she appeared to have experienced a relatively normative series of sexual experiences and relationships until age 23. Although she reported occasionally experiencing some pain or discomfort during intercourse, this did not recur and typically disappeared quickly if she changed position or became more aroused. At the age of 23, while breaking up with a boyfriend, she reported experiencing a series of vaginal/yeast infections that she treated on her own with over-the-counter medications. She diagnosed these infections both because intercourse became painful and she noticed some vaginal discharge.
Julie did not have intercourse again for several months. In the interim, she noticed that tampon insertion was much more uncomfortable than usual but still possible. The next time she had intercourse, Julie experienced a severe burning and cutting pain during penetration, although she was highly aroused. Despite this pain, she continued intercourse and experienced burning during urination for the next 36 hours. From this time on, Julie reported severe pain during attempted penetration on 100% of subsequent intercourse attempts. This pain often continued for a few hours after intercourse and was exacerbated by urination. Pain did not occur unless there was pressure to the vulvar area, e.g., intercourse, gynecological examination, tampon insertion, bicycle riding, tight jeans. Julie began to anticipate the pain and reported avoiding sexual and relationship opportunities; she also reported a marked decline in sexual desire. According to her family physician's report, Julie was in excellent health and was taking no medications. She also provided me with an extensive set of test results and physician reports indicating that she was free of infection, human papilloma virus (HPV), vulvovaginal abnormality or disease, or any chronic illness.
Although it is not mentioned in the DSM-IV, VVS was clearly described in the 19th century as "hyperesthesia of the vulva" (Skene, 1898). Why this syndrome appears to have been forgotten until recently is not clear but is probably the result of the fact that VVS and dyspareunia, in general, did not easily fit into the prevailing conceptual diagnostic models in either gynecology or psychiatry. In gynecology, the traditional diagnostic strategy for chronic dyspareunia has been to look for organic causes and in their absence assume a psychogenic etiology. Unfortunately, there are no reliable organically based diagnostic markers of VVS. Moreover, the routine gynecological examination does not carefully examine the vulvar vestibule where the pain of VVS is hypothesized to be localized.
It is interesting that psychiatric nosologies are similar to gynecological ones and also define dyspareunia in terms of the organic/psychogenic dichotomy. Strangely, these nosologies ignore the location of the pain. As a result, dyspareunia without organic cause is defined by the activity with which it interferes, i.e., sexual intercourse. Formally classifying a pain condition by the activity with which it interferes is an unusual nosological strategy since it results in the following diagnostic anomaly: both a deep pain felt close to the right ovary during thrusting and a superficial pain felt in the vulvovaginal area during penetration are classified under the same category of "sexual pain" (dyspareunia not due to a general medical condition, 302.76). What determines the sexual nature of this pain or why it is a sexual dysfunction altogether is not clear, since the pain can be easily induced in non-sexual situations.
Friedrich (1987), a gynecologist, helped to systematize the diagnosis of VVS by suggesting three criteria that have become the accepted gynecological standard: 1) severe pain on vestibular touch or attempted vaginal entry; 2) tenderness to pressure localized within the vulvar vestibule; and 3) physical findings confined to vestibular erythema of various degrees. The diagnosis is typically based on the woman's report of pain during penile penetration and confirmed by cotton swab palpation of the vulvar vestibule. Approximately 90% of women ultimately diagnosed with VVS describe their pain with adjectives like "burning" or "cutting" (Bergeron et al., 2001a). They also typically describe their pain as starting from the moment of penile penetration. This pain can be reproduced by a gynecologist lightly palpating the vulvar vestibule with a cotton swab. Such palpation is typically experienced as light pressure by the average woman but is exquisitely painful for women suffering from VVS. Cotton swab palpation of areas outside the vulvar vestibule result in minimal pain. So far, visual or colposcopic inspections of the vulva have not proved to be useful or reliable diagnostic methods for VVS.
Although these data suggest that VVS may be a distinctly diagnosable syndrome, there are still quite a number of unresolved practical and theoretical issues related to assessment. For example, there are numerous urogenital infections and dermatological conditions with symptoms that overlap with those of VVS (Foster, 2002; Stewart, 2002; Wesselmann et al., 1997). There are also accumulating data to indicate that VVS is sometimes hard to differentiate from vaginismus (de Kruiff et al., 2000; E.D. Reissing, M.D., et al., unpublished data, 2003). Finally, there are a number of chronic vulvar or urogenital pain syndromes referred to as essential or dysesthetic vulvodynia whose sufferers will also experience pain during intercourse and a positive cotton swab test. Usually, these vulvodynia sufferers can easily be differentiated from women with VVS by the fact that their pain is not limited to external stimulation but occurs spontaneously for long periods of time and often on a daily basis. It will often take careful and repeated multidisciplinary assessment to reliably determine whether a woman is suffering from VVS. Although women with VVS are often anxious, depressed or angry about their pain, this distress rarely reaches clinical levels (Meana et al., 1997). Currently available evidence suggests that these emotions are normal reactions to an upsetting and recurring pain experience that seriously threatens the quality and existence of intimate relationships. This distress must often be acknowledged and dealt with before problem-focused attempts at dealing with the pain are initiated. A careful assessment may require a detailed interview (regarding pain, sexual functioning, interpersonal relationships, coping attempts), a gynecological examination including the cotton swab test, exclusion of other possible problems and an assessment of the pelvic floor musculature.
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