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An Antidote to Factor Xa Inhibitors at Last!
Andexanet alfa is a recombinant factor Xa molecule that binds to and sequesters factor Xa inhibitors in the blood, making them unavailable to bind to native factor Xa.
In Workup for New-Onset AF, What and What Not to Order?
In new-onset atrial fibrillation there is good evidence for obtaining a troponin T level. High levels are associated with highest rates of stroke, embolism, and cardiac mortality.
Direct Thrombin Inhibitors May Pose Increased Risk of MI
Dabigatran was shown in post-hoc analysis of the RE-LY trial to be associated with an increased risk of MI compared with warfarin.
Does Rivaroxaban in Patients With AF Differ in Those With Prior MI?
Rivaroxaban when used to treat patients with atrial fibrillation who have had a previous MI is associated with higher risk for adverse events.
Warfarin, Aspirin, Both, or Neither: What Would You Prescribe?
Whether to prescribe an antiplatelet or antithrombotic agent for a patient who has AF but is otherwise healthy can be a difficult decision.
Paroxysmal Atrial Fibrillation: How to Safely Restore Sinus Rhythm?
Cardioversion for paroxysmal atrial fibrillation must include pre- and post-procedure anticoagulation to avoid thromboembolic risk.
In Patients With a Mechanical Valve, Which Agent for Oral Anticoagulation?
Only one agent can be used for anticoagulation in individuals with mechanical valves.
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