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Bipolar Disorder

Bipolar Disorder: Effective Personalized Strategies

Bipolar disorder is a biopsychosocial disorder, but mood-stabilizing medications are the backbone of treatment.

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Bipolar Disorder

New neuroanatomical studies demonstrate abnormalities in brain circuitry and anatomical disconnects between regions of the brain that help to explain the aberrations of emotion and reward processing in bipolar disorder.

Chronobiology—the science of daily (circadian), monthly, tidal, and seasonal rhythms—has undergone exponential growth in the past decade, with major discoveries at the molecular and neuroanatomic level.

Diagnosis and treatment problems for bipolar patients extend well beyond mere mood symptoms. These studies examine who needs care most, who is least likely to get it, and one way to improve adherence to treatment.

The authors-- both well-known specialists-- attempt to integrate the two fundamental ingredients of psychotherapy and pharmacology in the treatment of bipolar disorders.

New brain biomarker studies hint at an intriguing pathological mechanism for bipolar disorder. This kind of research is just what is needed, judging from recent editorials on the question.

Clinical applications for the most commonly used anticonvulsants are reviewed here, along with complications and recent findings for day-to-day practice. Also: an update on findings from research on anticonvulsants used less often, but which may be potentially beneficial.

Given the greater frequency of depression than manic episodes in bipolar disorder, what clues indicate bipolar disorder rather than unipolar depression?

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