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Bipolar Disorder

The Neural Basis of Bipolar Disorder

Highlights from the recent acceleration in understanding of the mechanisms of bipolar disorder.

From our archives:
Defining and Overcoming Treatment Resistance

Bipolar Disorder

Treating Bipolar Patients with Lithium

Lithium plays an important role in reducing morbidity and mortality associated with bipolar disorder. Psychiatrists can optimize the benefits of lithium by carefully choosing patients for long-term treatment and educating them about the risks and benefits.

New MRI studies of white matter show differences between bipolar with psychosis and schizophrenia, and distinguish unipolar from bipolar depression.

A comprehensive program had significant benefit for depression in bipolar patients living in the Netherlands. Another study highlights the poor quality of primary care for bipolar patients in one of the United States.

Media attention to bipolar and Internet-based information lead some people to decide (mistakently) that they have the condition. Correct assessment and affirming reassurance, studies snow, is what patients with mood instability want most.

The Neural Basis of Bipolar Disorder

Selected for clinical implications, here are some highlights from the recent acceleration in understanding of the mechanisms of bipolar disorder.

Animal and human studies confirm a role for aberrant development of neurons that control dopamine and serotonin in mood fluctuations in bipolar disorder.

It may be difficult to distinguish borderline personality disorder from bipolar, but the difference is crucial for appropriate treatment. A review details the features crucial to correct diagnosis.

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