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Personality Disorders: MedlinePlus
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Verkes Borderline Study: The Effect of Quetiapine on Borderline Personality Disordered Patients
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Borderline Personality Disorder
 
LATEST FEATURES
July 1, 2004
Borderline Personality Disorder: An Overview
Although the term borderline has been in clinical use since the late 1930s, it only became an official Axis II diagnosis in 1980 with the publication... More »
December 1, 2003
Suicidal Self-Injurious Behavior in People With BPD
Unlike other forms of self-injury, suicidal self-injury has special meaning, particularly in the context of borderline personality disorder. How is... More »
July 1, 2001
Psychoanalytic Treatment of Borderline Personality Disorder
After the recent decade of the brain and in the present era of evidence-based practice, psychoanalytic treatment of personality disorder is being... More »
July 1, 1999
Marsha Linehan: Dialectic Behavioral Therapy
For her work in establishing the Dialectic Behavioral Therapy (DBT) model for use with chronically suicidal individuals suffering from borderline... More »
July 1, 1999
Marsha Linehan: Dialectic Behavioral Therapy
For her work in establishing the Dialectic Behavioral Therapy (DBT) model for use with chronically suicidal individuals suffering from borderline... More »
Showing 31 - 35 of 35 results.
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MEDLINE
Defense mechanisms reported by patients with borderline personality disorder and axis II comparison subjects over 16 years of prospective follow-up: description and prediction of recovery.
pubmed.gov - 12/31/12
The authors assessed the defensive functioning of 290 patients with borderline personality disorder and compared it with that of 72 patients with other forms of axis II psychopathology over 16 years of prospective follow-up. They also assessed the relationship between time-varying defenses and recovery from borderline personality disorder.|The Defense Style Questionnaire, a self-report measure with demonstrated criterion validity and internal consistency, was initially administered at study entry. It was readministered at eight contiguous 2-year follow-up periods.|Borderline patients had significantly lower scores than axis II comparison subjects on one mature defense mechanism (suppression) and significantly higher scores on seven of the other 18 defenses studied: one neurotic-level defense (undoing), four immature defenses (acting out, emotional hypochondriasis, passive aggression, and projection), and two image-distorting/borderline defenses (projective identification and splitting)
Management of borderline personality disorder.
pubmed.gov - 11/19/12
23027916 2012 11 20 2013 01 17 1488-2329 184 17 Nov 20 CMAJ 1897-902 10.1503/cmaj.112055 Department of Psychiatry, Institute of Community and Family Psychiatry, Sir Mortimer B. Davis Jewish General Hospital, Montral, Que. robert.biskin@mcgill.ca
Diagnosing borderline personality disorder.
pubmed.gov - 11/5/12
22988153 2012 11 06 2013 01 16 1488-2329 184 16 Nov 6 CMAJ 1789-94 10.1503/cmaj.090618 Department of Psychiatry, Sir Mortimer B. Davis Jewish General Hospital, Montral, Quebec, Canada. robert.biskin@mcgill.ca Biskin Robert S RS Paris Joel J eng
Executive attention and personality variables in patients with frontal lobe damage.
pubmed.gov - 11/1/12
Executive Control is required to deal with novel situations or when an action plan is needed. This study aimed to highlight the executive attention deficits of patients with frontal lobe damage. To do so, the ANT-I task (Attention Network Test-Interactions) was administered for the first time to a group of 9 patients with frontal damage caused by traumatic brain injury (TBI) and a matched control group. This task made it possible to measure the three attentional networks proposed by Posner and Dehaene (1994) and their interactions. Results on the alerting and orienting networks did not show any significant differences between the groups. However, a significant effect of group on the executive control network was observed. In addition, participants' personality was assessed with a clinical inventory (the Millon Personality Inventory) that showed a significant positive correlation between borderline personality disorder and the conflict index. These results suggest that frontal lobe
Volumetric and topographic differences in hippocampal subdivisions in borderline personality and bipolar disorders.
pubmed.gov - 10/7/12
Hippocampal abnormalities may be implicated in the pathophysiology of mental disorders with affective symptoms such as borderline personality disorder (BPD) and bipolar disorder (BD). We aimed to investigate hippocampal morphology in BPD and BD patients, compared to 1:1 age- and sex-matched healthy controls (HC) using a three-dimensional mapping method. Manual tracing of the hippocampi on magnetic resonance imaging (MRI) images was performed on 26 patients with BPD (age: 3811; sex (f): 16 (61%)) and 15 with BD (age: 449; sex (f): 5 (33%)) and their age- and sex-matched HC (for BPD: n=26; age: 3811; sex (f): 16 (61%); for BD: n=15; age: 449; sex (f): 5 (33%)). Compared to their reference groups, BPD patients showed smaller hippocampal volume bilaterally. The BD group showed significantly smaller right hippocampal volumes. In the surface maps, alterations were localized to different hippocampal sectors for the two groups: the CA1 regions and subiculum, bilaterally, in BPD, and
 
JOURNAL SCAN
Amygdala and hippocampal volume reductions as candidate endophenotypes for borderline personality disorder: a meta-analysis of magnetic resonance imaging studies.
pubmed.gov - 3/31/12
Borderline personality disorder (BPD) is a genetically influenced psychiatric illness with disruptions in neural systems supporting cognition and emotion regulation. Volumetric decreases of the hippocampus and amygdala may characterize BPD and serve as putative endophenotypes for the illness. The purpose of the present study was to evaluate whether the magnitude of these volume reductions and their associations with state-of-illness factors and psychiatric disorders which often co-occur with BPD warrant their consideration as potential endophenotypes. Volumetric magnetic resonance imaging results from 11 studies comprising 205 BPD patients and 222 healthy controls were quantitatively synthesized using meta-analytic techniques. Patients showed an average 11% and 13% decrease in the size of the hippocampus and amygdala, respectively. These volumetric differences were not attenuated in patients being treated with psychotropic medications. Comorbid depression, post-traumatic stress
Psychological therapies for people with borderline personality disorder.
pubmed.gov - 1/1/12
Psychotherapy is regarded as the first-line treatment for people with borderline personality disorder. In recent years, several disorder-specific interventions have been developed. This is an update of a review published in the Cochrane Database of Systematic Reviews in 2006.|To assess the effects of psychological interventions for borderline personality disorder (BPD).|We searched the following databases: CENTRAL 2010(3), MEDLINE (1950 to October 2010), EMBASE (1980 to 2010, week 39), ASSIA (1987 to November 2010), BIOSIS (1985 to October 2010), CINAHL (1982 to October 2010), Dissertation Abstracts International (31 January 2011), National Criminal Justice Reference Service Abstracts (15 October 2010), PsycINFO (1872 to October Week 1 2010), Science Citation Index (1970 to 10 October 2010), Social Science Citation Index (1970 to 10 October 2010), Sociological Abstracts (1963 to October 2010), ZETOC (15 October 2010) and the metaRegister of Controlled Trials (15 October 2010). In
Hippocampal volume in borderline personality disorder with and without comorbid posttraumatic stress disorder: a meta-analysis.
pubmed.gov - 10/1/11
Several studies have found a reduction in hippocampal volume in borderline personality disorder (BPD) patients.|In order to investigate the degree to which comorbid posttraumatic stress disorder (PTSD) could account for reduction in hippocampal volume in these patients, we conducted a systematic review and meta-analysis of studies that compared hippocampal volume in BPD patients with and without PTSD relative to healthy controls.|Seven articles, involving 124 patients and 147 controls, were included. We found a statistically significant reduction for the left and right hippocampus. Data from the four studies that discriminated BPD patients with and without PTSD indicate that hippocampal volumes were reduced bilaterally in BPD patients with PTSD, relative to healthy controls, but that results were mixed for BPD patients without PTSD, relative to healthy controls.|Results from this meta-analysis suggest that hippocampal volumes are reduced in patients with BPD, relative to healthy
Antipsychotics, antidepressants, anticonvulsants, and placebo on the symptom dimensions of borderline personality disorder: a meta-analysis of randomized controlled and open-label trials.
pubmed.gov - 10/1/11
The aim of this study was to quantitatively review randomized controlled trials (RCTs) and open-label trials analyzing the efficacy of antidepressants, mood stabilizers, and antipsychotics for the treatment of the core symptoms of borderline personality disorder (BPD). Using a similar meta-analytic approach, the efficacy of placebo on the same core symptoms of BPD was evaluated. The risk of discontinuation of each of the medication classes reported in the studies was also analyzed to establish the major causes of discontinuation. MEDLINE (1966 to June 2010) and EMBASE (1980 to June 2010) databases were systematically searched to identify relevant RCTs and open studies. The primary outcome was improvement in the specific core symptoms of the disorder: affective dysregulation, impulsive-behavioral dyscontrol, and cognitive-perceptual symptoms. Evidence from RCTs and open studies suggests that drug treatment, especially with mood stabilizers and antipsychotics, may be effective for
A (re)-evaluation of the symptom structure of borderline personality disorder.
pubmed.gov - 9/1/11
Despite evidence of significant symptom heterogeneity and excessive diagnostic comorbidity, many contend that borderline personality disorder (BPD) is unidimensional, an assumption that rests primarily on results from factor analytic investigations of BPD symptom criteria. We note several limitations in the literature and argue that the symptom structure of BPD can be best clarified by using both factor analytic techniques and examining the BPD symptom dimensions in relation to external criteria (that is, personality traits). Our goals were to: examine if the symptoms of BPD are best conceptualized as unidimensional or multidimensional, and determine the extent to which personality traits account for any symptom dimensions that underlie BPD.|All published structural models of the BPD symptom criteria were identified and tested for statistical fit using confirmatory factor analysis in a sample of 373 patients who had completed the Structured Clinical Interview for the Diagnostic and
 
PRACTICE GUIDELINES
Microsoft Word
www.aacap.org -
9/8/2011 Please Call Speaker Boehner Ask Him to Allow a Vote on The Combating Autism Reauthorization Act Before it Expires on September 30th The Combating Autism Act of 2006 ... If The Combating Autism Reauthorization Act ( CARA, H.R. 2005) is not passed
National Guideline Clearinghouse | Best evidence statement (BESt). Craniosacral therapy for children with autism and/or sensory processing disorder.
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Best evidence statement (BESt). Craniosacral therapy for children with autism and/or sensory processing disorder.
National Guideline Clearinghouse | Best evidence statement (BESt). The use of video-based modeling in teaching daily living skills to children with autism.
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Best evidence statement (BESt). The use of video-based modeling in teaching daily living skills to children with autism.
National Guideline Clearinghouse | Best evidence statement (BESt). Outcomes assessment tool for children with autism spectrum disorder (ASD).
www.guidelines.gov -
Best evidence statement (BESt). Outcomes assessment tool for children with autism spectrum disorder (ASD).
National Guideline Clearinghouse | Best evidence statement (BESt). Use of sensory assessment tools with children diagnosed with autism spectrum disorder (ASD).
www.guidelines.gov -
Best evidence statement (BESt). Use of sensory assessment tools with children diagnosed with autism spectrum disorder (ASD).



 
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