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Home » Child and Adolescent Psychiatry

Psychiatric Times. Vol. 26 No. 10
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CHILD AND ADOLESCENT PSYCHIATRY 

Eating Disorders in Children and Adolescents

By James Lock, MD, PhD | October 8, 2009

Dr Lock is professor of psychiatry and behavioral sciences at the Lucille Packard Children’s Hospital, Stanford University in Palo Alto, Calif. He reports that he has received research support from the NIH, the Davis Foundation, and the Lucille Packard Children’s Foundation; he receives royalties from Guilford Press for published books on eating disorders.

About the photographer: Bruce Martin resides in Jupiter, Fla. A graduate of the State University of New York at Syracuse with a degree in landscape architecture, he has assembled a large body of photographic work as an independent photographer from his travels and studies throughout the world. While his interests are primarily in nature photography, his art encompasses planning, implementation, and management of large and sustainable environments through landscape design. He can be reached at brucedebimartin@bellsouth.net.


A study that compares family therapy, individual supportive therapy, and CBT for adolescents with bulimia nervosa is just getting under way at the University of Chicago and Stanford University. When completed, it will be the largest study of adolescent bulimia nervosa undertaken. It will provide information on whether individual supportive therapy, CBT, or family therapy is the most effective approach for the disorder and will help identify patients who might benefit differentially from one treatment.

Conclusion

(MORE: Sexual Minority Identity Development)

While clinicians await the results of these trials, the current evidence suggests that for adolescents with eating disorders, the best available treatment is family therapy aimed at helping parents manage their child’s eating disorder symptoms.32 While the evidence for the superiority of this form of family therapy over other treatments is still limited, the data suggest that it is effective in many cases. Family therapy also appears to be useful clinically in nonresearch populations, and manualized versions of the approach are available.30,33,34 At the same time, there is undoubtedly an important role for other therapies, including individual therapy for adolescents with anorexia nervosa and bulimia nervosa, especially in situations where family therapy is not an option.29

Medications for eating disorders in children and adolescents should be reserved for those with comorbid conditions (eg, anxiety, depression) or for those who are not responsive to psychosocial treatments. The use of medication for the treatment of adolescents with anorexia nervosa—even for comorbid conditions—might best be deferred until weight is normalized to help ensure that anxiety, obsessive-compulsive behaviors and thoughts, and depressed affect are not primarily nutritionally or behaviorally based.

Among the many challenges clinicians face is developing specific expertise in treating child and adolescent eating disorders. Most eating disorder specialists focus on treating adults, and few have sufficient training or appreciation of developmental differences in younger patients who have an eating disorder. Furthermore, many nonspecialist clinicians have little training in the treatment of eating disorders, particularly in family therapy. Although there are regional centers of excellence in the treatment of child and adolescent eating disorders, these are few in number and are located mostly in urban centers. Reliance on hospital and residential treatment is, in part, a result of these limitations of trained professionals. Efforts to address these disparities by integrating eating disorder treatment training in clinical training programs, use of distance learning, and distance therapy are needed.

References
1. Hoek HW, Hoeken D. Review of prevalence and incidence of eating disorders. Int J Eat Disord. 2003;34:383-396.
2. Bravender T, Bryant-Waugh R, Herzog D, et al; Workgroup for the Classification of Eating Disorders in Children and Adolescents. Int J Eat Disord. 2007;40:S117-S122.
3. Nicholls D, Randall CD, Lask B. Selective eating: symptom disorder or normal variant? Clin Child Psychol Psychiatry. 2001;6:257-270.
4. Bryant-Waugh R, Lask B. Overview of eating disorders. In: Lask B, Bryant-Waugh R, eds. Eating Disorders in Childhood and Adolescence. 3rd ed. Hove, UK: Routledge; 2007:35-50.
5. Centers for Disease Control and Prevention. CDC Growth Charts for the United States: Development and Methods. Atlanta: Centers for Disease Control and Prevention, US Dept of Health and Human Services; 2002.
6. Marcus MD, Kalarchian MA. Binge eating in children and adolescents. Int J Eat Disord. 2003;(34 suppl):S47-S57.
7. Turner H, Bryant-Waugh R. Eating disorder not otherwise specified (EDNOS): profiles of clients presenting at a community eating disorder service. Eur Eat Disord Rev. 2004;12:18-26.
8. Bulik CM, Berkman ND, Brownley, KA, et al. Anorexia nervosa treatment: a systematic review of randomized controlled trials. Int J Eat Disord. 2007;40:310-320.
9. Walsh BT, Kaplan AS, Attia E, et al. Fluoxetine(Drug information on fluoxetine) after weight restoration in anorexia nervosa: a randomized controlled trial. JAMA. 2006;295:2605-2612.
10. Couturier J, Lock J. What is remission in adolescent anorexia nervosa? A review of various conceptualizations and a quantitative analysis. Int J Eat Disord. 2006;39:175-183.
11. Couturier J, Lock J. A review of medication use for children and adolescents with eating disorders. J Can Acad Child Adolesc Psychiatry. 2007;16:173-176.
12. Agras WS, Walsh T, Fairburn CG, et al. A multicenter comparison of cognitive-behavioral therapy and interpersonal psychotherapy for bulimia nervosa. Arch Gen Psychiatry. 2000;57:459-466.
13. le Grange D, Crosby R, Rathouz PJ, Leventhal BL. A randomized controlled comparison of family-based treatment and supportive psychotherapy for adolescent bulimia nervosa. Arch Gen Psychiatry. 2007;64:1049-1056.
14. Schmidt U, Lee S, Beecham J, et al. A randomized controlled trial of family therapy and cognitive-behavior therapy–guided self-care for adolescents with bulimia nervosa and related conditions. Am J Psychiatry. 2007;164:591-598.
15. Lock J. Adjusting cognitive -behavioral therapy for adolescent bulimia nervosa: results of a case series. Am J Psychother. 2005;59:267-281.
16. Walsh BT, Wilson GT, Loeb KL, et al. Medication and psychotherapy in the treatment of bulimia nervosa. Am J Psychiatry. 1997;154:523-531.
17. Koran LM, Agras WS, Rossiter EM, et al. Comparing the cost-effectiveness of psychiatric treatments: bulimia nervosa. Psychiatry Res. 1995;58:13-21.
18. Kotler LA, Devlin MJ, Davies M, Walsh BT. An open trial of fluoxetine for adolescents with bulimia nervosa. J Child Adolesc Psychopharmacol. 2003;13:329-335.
19. Lock J, Giammona A. Severe somatoform disorder in adolescence: a case series using a rehabilitation model for intervention. Clin Child Psychol Psychiatry. 1999;4:341-351.
20. Meads C, Gold L, Burls A. How effective is outpatient care compared to inpatient care for the treatment of anorexia nervosa? A systematic review. Eur Eat Disord Rev. 2001;9:229-241.
21. Crisp AH, Norton K, Gowers S, et al. A controlled study of the effect of therapies aimed at adolescent and family psychopathology in anorexia nervosa. Br J Psychiatry. 1991;159:325-333.
22. Gowers S, Clark A, Roberts C, et al. Clinical effectiveness of treatments for anorexia nervosa in adolescents. Br J Psychiatry. 2007;191:427-435.
23. Byford S, Barrett B, Roberts C, et al. Economic evaluation of a randomised controlled trial for anorexia nervosa in adolescents. Br J Psychiatry. 2007;191:436-440.
24. Frisch MJ, Herzog DB, Franko DL. Residential treatment for eating disorders. Int J Eat Disord. 2006;39:434-442.
25. Lock J, Agras WS, Bryson S, Kraemer HC. A comparison of short- and long-term family therapy for adolescent anorexia nervosa. J Am Acad Child Adolesc Psychiatry. 2005;44:632-639.
26. Lock J, Couturier J, Agras WS. Comparison of long-term outcomes in adolescents with anorexia nervosa treated with family therapy. J Am Acad Child Adolesc Psychiatry. 2006;45:666-672.
27. Golden NH, Katzman DK, Kreipe RE, et al. Eating disorders in adolescents: position paper of the Society for Adolescent Medicine. J Adolesc Health. 2003;33:496-503.
28. American Academy of Pediatrics; Committee on Adolescence. Identifying and treating eating disorders. Pediatrics. 2003;111:204-211.
29. Fitzpatrick K, Moye A, Hostee R, et al. Adolescent-focused therapy for adolescent anorexia nervosa. J Contemp Psychother. In press.
30. Lock J, le Grange D, Agras WS, Dare C. Treatment Manual for Anorexia Nervosa: A Family-Based Approach. New York: Guilford Publications, Inc; 2001.
31. Pote H, Stratton P, Cottrell D, et al. Systemic family therapy can be manualized: research process and findings. J Fam Ther. 2003;25:236-262.

 

 

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Also in this Special Report

Eating Disorders in Children and Adolescents

Anxiety Disorders in Children and Adolescents

Continuation Treatment and Relapse Prevention in Pediatric Depression

Sexual Minority Identity Development





References

1. Hoek HW, Hoeken D. Review of prevalence and incidence of eating disorders. Int J Eat Disord. 2003; 34:383-396.
2. Bravender T, Bryant-Waugh R, Herzog D, et al; Workgroup for the Classification of Eating Disorders in Children and Adolescents. Int J Eat Disord. 2007; 40:S117-S122.
3. Nicholls D, Randall CD, Lask B. Selective eating: symptom disorder or normal variant? Clin Child Psychol Psychiatry. 2001;6:257-270.
4. Bryant-Waugh R, Lask B. Overview of eating disorders. In: Lask B, Bryant-Waugh R, eds. Eating Disorders in Childhood and Adolescence. 3rd ed. Hove, UK: Routledge; 2007:35-50.
5. Centers for Disease Control and Prevention. CDC Growth Charts for the United States: Development and Methods. Atlanta: Centers for Disease Control and Prevention, US Dept of Health and Human Services; 2002. http://www.cdc.gov/growthcharts/percentile_data_files.htm.
6. Marcus MD, Kalarchian MA. Binge eating in children and adolescents. Int J Eat Disord. 2003;(34 suppl):S47-S57.
7. Turner H, Bryant-Waugh R. Eating disorder not otherwise specified (EDNOS): profiles of clients presenting at a community eating disorder service. Eur Eat Disord Rev. 2004;12:18-26.
8. Bulik CM, Berkman ND, Brownley, KA, et al. Anorexia nervosa treatment: a systematic review of randomized controlled trials. Int J Eat Disord. 2007;40: 310-320.
9. Walsh BT, Kaplan AS, Attia E, et al. Fluoxetine after weight restoration in anorexia nervosa: a randomized controlled trial. JAMA. 2006;295:2605-2612.
10. Couturier J, Lock J. What is remission in adolescent anorexia nervosa? A review of various conceptualizations and a quantitative analysis. Int J Eat Disord. 2006;39:175-183.
11. Couturier J, Lock J. A review of medication use for children and adolescents with eating disorders. J Can Acad Child Adolesc Psychiatry. 2007;16:173-176.
12. Agras WS, Walsh T, Fairburn CG, et al. A multicenter comparison of cognitive-behavioral therapy and interpersonal psychotherapy for bulimia nervosa. Arch Gen Psychiatry. 2000;57:459-466.
13. le Grange D, Crosby R, Rathouz PJ, Leventhal BL. A randomized controlled comparison of family-based treatment and supportive psychotherapy for adolescent bulimia nervosa. Arch Gen Psychiatry. 2007;64: 1049-1056.
14. Schmidt U, Lee S, Beecham J, et al. A randomized controlled trial of family therapy and cognitive-behavior therapy–guided self-care for adolescents with bulimia nervosa and related conditions. Am J Psychiatry. 2007;164:591-598.
15. Lock J. Adjusting cognitive-behavioral therapy for adolescent bulimia nervosa: results of a case series. Am J Psychother. 2005;59:267-281.
16. Walsh BT, Wilson GT, Loeb KL, et al. Medication and psychotherapy in the treatment of bulimia nervosa. Am J Psychiatry. 1997;154:523-531.
17. Koran LM, Agras WS, Rossiter EM, et al. Comparing the cost-effectiveness of psychiatric treatments: bulimia nervosa. Psychiatry Res. 1995;58:13-21.
18. Kotler LA, Devlin MJ, Davies M, Walsh BT. An open trial of fluoxetine for adolescents with bulimia nervosa. J Child Adolesc Psychopharmacol. 2003;13: 329-335.
19. Lock J, Giammona A. Severe somatoform disorder in adolescence: a case series using a rehabilitation model for intervention. Clin Child Psychol Psychiatry. 1999;4:341-351.
20. Meads C, Gold L, Burls A. How effective is outpatient care compared to inpatient care for the treatment of anorexia nervosa? A systematic review. Eur Eat Disord Rev. 2001;9:229-241.
21. Crisp AH, Norton K, Gowers S, et al. A controlled study of the effect of therapies aimed at adolescent and family psychopathology in anorexia nervosa. Br J Psychiatry. 1991;159:325-333.
22. Gowers S, Clark A, Roberts C, et al. Clinical effectiveness of treatments for anorexia nervosa in adolescents. Br J Psychiatry. 2007;191:427-435.
23. Byford S, Barrett B, Roberts C, et al. Economic evaluation of a randomised controlled trial for anorexia nervosa in adolescents. Br J Psychiatry. 2007;191:436-440.
24. Frisch MJ, Herzog DB, Franko DL. Residential treatment for eating disorders. Int J Eat Disord. 2006;39:434-442.
25. Lock J, Agras WS, Bryson S, Kraemer HC. A comparison of short- and long-term family therapy for adolescent anorexia nervosa. J Am Acad Child Adolesc Psychiatry. 2005;44:632-639.
26. Lock J, Couturier J, Agras WS. Comparison of long-term outcomes in adolescents with anorexia nervosa treated with family therapy. J Am Acad Child Adolesc Psychiatry. 2006;45:666-672.
27. Golden NH, Katzman DK, Kreipe RE, et al. Eating disorders in adolescents: position paper of the Society for Adolescent Medicine. J Adolesc Health. 2003;33:496-503.
28. American Academy of Pediatrics; Committee on Adolescence. Identifying and treating eating disorders. Pediatrics. 2003;111:204-211.
29. Fitzpatrick K, Moye A, Hostee R, et al. Adolescent-focused therapy for adolescent anorexia nervosa. J Contemp Psychother. In press.
30. Lock J, le Grange D, Agras WS, Dare C. Treatment Manual for Anorexia Nervosa: A Family-Based Approach. New York: Guilford Publications, Inc; 2001.
31. Pote H, Stratton P, Cottrell D, et al. Systemic family therapy can be manualized: research process and findings. Journal of Family Therapy. 2003;25:236-262.
32. National Institute for Health and Clinical Excel-lence. Eating disorders: core interventions in the treatment and management of anorexia nervosa, bulimia nervosa, and binge eating disorder. London: NICE; 2004. http://www.nice.org.uk/CG009. Accessed September 17, 2009.
33. Loeb KL, Walsh BT, Lock J, et al. Open trial of family-based treatment for full and partial anorexia nervosa in adolescence: evidence of successful dissemination. J Am Acad Child Adolesc Psychiatry. 2007;46:792-800.
34. le Grange D, Lock J. Treating Bulimia in Adolescents. New York: Guilford Press; 2007.


 
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