Inflammation and Treatment Resistance in Major Depression: The Perfect Storm

Inflammation and Treatment Resistance in Major Depression: The Perfect Storm

Clinical predictors of treatment resistance related to inflammationTable 1
Cytokines circumvent mechanisms of action of conventional antidepressantsreFigure 2
Translational targets for inflammation and treatment-resistant depressionTable 2

All other clinicians will either receive a CME Attendance Certificate or may choose any of the types of CE credit being offered.

Premiere Date: September 20, 2013
Expiration Date: September 20, 2014

This activity offers CE credits for:
1. Physicians (CME)
2. Other

Activity Goal

The goal of this activity is to present information on the role that inflammation plays in treatment-resistant depression.

Learning Objectives

At the end of this CE activity, participants should be able to:

1. Understand the correlation between inflammation and treatment-resistant depression.

2. Describe the clinical factors associated with treatment non-response and how these factors correlate with inflammation.

3. Identify the mechanisms that lead to nonresponse.

Target Audience

This continuing medical education activity is intended for psychiatrists, psychologists, primary care physicians, physician assistants, nurse practitioners, and other health care professionals who seek to improve their care for patients with mental health disorders.

Credit Information

CME Credit (Physicians): This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of CME Outfitters, LLC, and Psychiatric Times. CME Outfitters, LLC, is accredited by the ACCME to provide continuing medical education for physicians.

CME Outfitters designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Note to Nurse Practitioners and Physician Assistants: AANPCP and AAPA accept certificates of participation for educational activities certified for AMA PRA Category 1 Credit.

Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CME/CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CME/CE activity. CME Outfitters, LLC, has evaluated, identified, and attempted to resolve any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer-review process.

The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Charles L. Raison, MD, reports that he is a steering committee member for NACCME, and he is involved in the creation of CME material for NACCME and CME Incite.

Jennifer C. Felger, PhD, has no disclosures to report.

Andrew H. Miller, MD, has no disclosures to report.

Ebrahim Haroon, MD (peer/content reviewer), reports that he receives grant support from the National Institute of Mental Health and the National Center for Complementary and Alternative Medicine.

Applicable Psychiatric Times staff have no disclosures to report.

Unlabeled Use Disclosure

Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CME Outfitters, LLC, and the faculty do not endorse the use of any product outside of the FDA-labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

Questions about this activity? Call us at 877.CME.PROS (877.263.7767).


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