Psychotropic medications and renal failure

January 3, 2012

Antidepressants - SSRIs

Escitalopram (Lexapro) Citalopram (Celexa) Fluoxetine (Prozac, Sarafem) Fluvoxamine (Luvox) Paroxetine (Paxil) Sertraline (Zoloft)

Antidepressants - Tricyclics

Amitriptyline (Elavil) Clomipramine (Anafranil) Desipramine (Norpramin) Doxepin (Sinequan) Imipramine (Tofranil) Nortryptiline (Aventyl, Pamelor)

Antidepressants - Other

Bupropion (Wellbutrin, Zyban) Duloxetine (Cymbalta) Maprotiline (Ludiomil) Mirtazapine (Remeron) Venlafaxine (Effexor)

Antimanic agents

Lithium (Eskalith, Lithobid, Lithonate)

Antipsychotics - Atypical^a

Aripiprazole (Abilify) Clozapine (Clozaril) Olanzapine (Zyprexa) Quetiapine (Seroquel) Risperidone (Risperdal) Ziprasidone (Geodon)

Antipsychotics - Typical

Chlorpromazine (Thorazine) Haloperidol (Haldol)

Anxiolytics and Hypnotics

Alprazolam (Xanax) Buspirone (Buspar) Lorazepam (Ativan) Midazolam (Versed) Oxazepam (Serax) Temazepam (Restoril) Eszopiclone (Lunesta) Ramelteon (Rozerem) Zaleplon (Sonata) Zolpidem (Ambien)

Anticonvulsants

Carbamazepine (Tegretol) Gabapentin (Neurontin) Lamotrigine (Lamictil) Oxcarbazepine (Trileptal) Phenobarbital (Luminal) Phenytoin (Dilantin) Pregabalin (Lyrica) Topirimate (Topomax) Valproic acid (valproate or divalproex) (Depakene, Depakote)

Footnote: ESRD, end-stage renal disease; H, hemodialysis; AUC, area under curve; CYP2D6, cytochrome P-450 2D6; CAPD, continuous ambulatory peritoneal dialysis; TDM, therapeutic drug monitoring; XR, extended-release; CrCl, creatinine clearance; CVVH, continuous veno-venous hemofiltration. ^a All atypical antipsychotics have risks for dyslipidemia, weight gain, insulin resistance, diabetes mellitus and metabolic syndrome, and are contra-indicated for dementia-related psychosis.

by Joseph Calles | July 11, 2012 11:03 PM EDT

This is very helpful. I did notice that when I clicked on "aripiprazole," it did not link to another page. Did anyone else have this experience? Does anyone have the renal-related info on aripiprazole?

by susan kweskin | July 13, 2012 12:26 PM EDT

Thanks Dr. Calles.....we've fixed the link; if you click on aripiprazole, the information you are looking for should appear.

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Psychotropic medications and renal failure

Antidepressants - SSRIs

Antidepressants - Tricyclics

Antidepressants - Other

Antimanic agents

Antipsychotics - Atypical^a

Antipsychotics - Typical

Anxiolytics and Hypnotics

Anticonvulsants

Join the Conversation

Psychotropic medications and renal failure

Antidepressants - SSRIs

Antidepressants - Tricyclics

Antidepressants - Other

Antimanic agents

Antipsychotics - Atypicala

Antipsychotics - Typical

Anxiolytics and Hypnotics

Anticonvulsants

Join the Conversation

Antipsychotics - Atypical^a