Answer key:
1. C
2. A
3. A
4. B
5. A
6. A
7. B
8. B
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Psychiatric Times. Vol. 29 No. 9
MINE YOUR MIND
Alcohol Disorders: Practical Tips From New Research
By Mark J. Niciu Jr, MD, PhD and Ismene Petrakis, MD |
September 7, 2012
Dr Niciu is Clinical Research Fellow at the NIMH in Bethesda, Md; Dr Petrakis is Professor of Psychiatry at the Yale School of Medicine, New Haven, Conn, and Chief of Psychiatry at the VA Connecticut Healthcare System in West Haven, Conn. The authors report no conflicts of interest concerning the subject matter of this article.
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Family history and antisocial traits moderate naltrexone’s effects on heavy drinking in alcoholics. Exp Clin Psychopharmacol. 2007;15:272-281. 27. Bond C, LaForge KS, Tian M, et al. Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci U S A.1998;95:9608-9613. 28.Oslin DW, Berrettini W, Kranzler HR, et al. A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology. 2003;28:1546-1552. 29. Anton RF, Oroszi G, O’Malley S, et al. An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Arch Gen Psychiatry. 2008;65:135-144. 30. Rösner S, Hackl-Herrwerth A, Leucht S, et al. 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Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence. Neuropsychopharmacology. 2012;37:996-1004. |
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