Psychiatric Times.
No. 6
Critical Issues in Perinatal Psychiatric Emergency Care
By Linda H. Chaudron, MD, MS |
May 1, 2006
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Table 2
Risks and benefits of psychiatric treatment
during pregnancy |
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Risks |
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Treatment options |
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• Untreated mental illness
- Safety of the mother
(self-harm, suicidality)
- Safety of fetus (self-induced termination)
- Malnutrition
- Refusal of prenatal care
- Precipitate or premature delivery
- Drug and alcohol(Drug information on alcohol) use
- Over-the-counter/herbal
self-treatment
- Low birth weight
- Long-term effects of anxiety/hypothalamic-pituitary-adrenal
axis changes on fetus/child
• Medication
- Physical anomalies (major and minor)
- Behavioral teratogenicity
- Cognitive/neurologic development
- Maternal side effects
- Pregnancy loss
- Fetal/neonatal withdrawal
and toxicity
• Alternatives
- Electroconvulsive therapy
- Hospitalization
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• No treatment
• Psychotherapy
• Prescription medication
• Combination psychotherapy and medication
• Hospitalization—inpatient or partial
• Electroconvulsive therapy
• Alternative treatments, such as light therapy,
omega-3 fatty acids
What affects and guides the decisions?
• Patient’s wishes and fears
• Severity of current illness
• Medication(s) needed
- Monotherapy versus polytherapy
- High-risk versus low-risk medication
- Dose required
- As-needed versus continuous use
• Patient’s psychiatric history
- Severity
- Recurrences when untreated
- Treatment response
• Patient’s triggers
• Family, partner support/opinions about treatment
• Ob/gyn, pediatrician opinions about treatment |
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Drugs Mentioned in This Article
Amitriptyline (Elavil, Endep)
Aripiprazole (Abilify)
Carbamazepine (Carbatrol, Tegretol, others)
Citalopram (Celexa)
Fluoxetine (Prozac)
Lamotrigine (Lamictal)
Lithium (Eskalith)
Nortriptyline (Aventyl, Pamelor)
Olanzapine (Zyprexa)
Paroxetine (Paxil)
Quetiapine (Seroquel)
Risperidone (Risperdal)
Sertraline (Zoloft)
Valproic acid (Depakote, Valproate, others)
Venlafaxine (Effexor)
Ziprasidone (Geodon)