The American Diabetes Association workgroup on diabetes and second-generation antipsychotic agents, of which Dr. Correll is a member, may be publishing revised recommendations in 2007 on the basis on new data and a more extensive review of the literature, he said. The current recommendations were published in 2004.
The coming year should bring more clinical trial data on which combinations of antidepressants are most effective in adults, said Robert Freedman, M.D., editor of the American Journal of Psychiatry, published by the American Psychiatric Association.
An important story from 2006 was publication of results from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study, Dr. Freedman said.
The study found that only about a third of depressed patients responded to initial treatment with a selective serotonin re-uptake inhibitor (SSRI), he said. Furthermore, the study failed to identify any clearly superior drug for treatment-resistant depression.