The median times to discontinuation reflected the same picture:
- Risperdal stayers remained on the drug for 8.4 months
- Zyprexa switchers lasted 7.7 months
- Risperdal switchers lasted 4.7 months.
Because of a relative lack of discontinuations, the researchers were unable to pin down the median time for Zyprexa stayers, but said it was greater than 11.6 months with 95% certainty.
Because of the size of the effect, the researchers re-analyzed the original CATIE data without the stayers and found that the overall picture was unchanged, although because of the smaller sample size, statistical significance was weakened.
