Dr. Karam-Hage is clinical assistant professor of psychiatry at the University of Michigan. He is also medical director of Chelsea Arbor Addiction Treatment Center, a joint program between the University of Michigan and Chelsea Community Hospital.
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Psychiatric Times. Vol. 21 No. 2 Treating Insomnia in Patients With Substance Use/Abuse Disorders
By Maher Karam-Hage, M.D. |
February 1, 2004
ReferencesAldrich MS (1998), Effects of alcohol on sleep. In: Alcohol Problems and Aging. NIAAA Research Monograph No. 33. Lisansky Gomberg ES, Hegedus AM, Zucker RA, eds. NIH Pub. No. 98-4163. Bethesda, Md.: NIAAA. Brower KJ (2001), Alcohol's effects on sleep in alcoholics. Alcohol Res Health 25(2):110-125. Brower KJ, Aldrich MS, Hall JM (1998), Polysomnographic and subjective sleep predictors of alcoholic relapse. Alcohol Clin Exp Res 22(8):1864-1871. Brower KJ, Aldrich MS, Robinson EA et al. (2001), Insomnia, self-medication, and relapse to alcoholism. Am J Psychiatry 158(3):399-404. Brower KJ, Kim HM, Karam-Hage M et al. (2003), A double-blind randomized clinical trial of gabapentin vs. placebo for treating alcohol dependence. Biol Psychiatry 53(8S):84S-85S. Ciraulo DA, Nace EP (2000), Benzodiazepine treatment of anxiety or insomnia in substance abuse patients. Am J Addict 9(4):276-279; discussion 280-284. Eder DN (2002), CEE-03-310 CeNeS pharmaceuticals. Curr Opin Investig Drugs 3(2):284-288. Gillin JC, Smith TL, Irwin M et al. (1994), Increased pressure for rapid eye movement sleep at time of hospital admission predicts relapse in nondepressed patients with primary alcoholism at 3-month follow-up. Arch Gen Psychiatry 51(3):189-197. Greeff AP, Conradie WS (1998), Use of progressive relaxation training for chronic alcoholics with insomnia. Psychol Rep 82(2):407-412. Hadley S, Petry JJ (2003), Valerian. Am Fam Physician 67(8):1755-1758. Karam-Hage M, Brower KJ (2000), Gabapentin treatment for insomnia associated with alcohol dependence. Am J Psychiatry 157(1):151 [letter]. Karam-Hage M, Brower KJ (2003), Open pilot study of gabapentin versus trazodone to treat insomnia in alcoholic outpatients. Psychiatry Clin Neurosci 57(5):542-544. Kupfer DJ, Reynolds CF 3rd (1997), Management of insomnia. N Engl J Med 336(5):341-346 [see comment]. Landolt HP, Roch C, Dijk DJ, Borbely AA (1996), Late-afternoon ethanol intake affects nocturnal sleep and the sleep EEG in middle-aged men. J Clin Psychopharmacol 16(6):428-436. Liappas IA, Malitas PN, Dimopoulos NP et al. (2003), Zolpidem dependence case series: possible neurobiological mechanisms and clinical management. J Psychopharmacol 17(1):131-135. Marzanatti M, Monopoli A, Trampus M, Ongini E (1989), Effects of nonsedating histamine H1-antagonists on EEG activity and behavior in the cat. Pharmacol Biochem Behav 32(4):861-866. NIAAA (1998), Alcohol Alert: Alcohol and Sleep. Pub 98-41. Available at: www.niaaa.nih.gov/publications/aa41.htm. AccessedJan. 8, 2004. Roehrs T, Roth T (1995), Alcohol-induced sleepiness and memory function. Alcohol Health Res World 19(2):130-135. Rush CR, Baker RW, Wright K (1999), Acute behavioral effects and abuse potential of trazodone, zolpidem and triazolam in humans. Psychopharmacology (Berl) 144(3):220-233. Schmitz MM, Sepandj A, Pichler PM, Rudas S (1996), Disrupted melatonin-secretion during alcohol withdrawal. Prog Neuropsychopharmacol Biol Psychiatry 20(6):983-995. Smith MT, Perlis ML, Park A et al. (2002), Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia. Am J Psychiatry 159(11):5-11. Thase ME (1999), Antidepressant treatment of the depressed patient with insomnia. J Clin Psychiatry 60(suppl 17):28-31; discussion 46-48. Vitiello MV (1997), Sleep, alcohol and alcohol abuse. Addict Biol 2(2):151-158. |
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