Furthermore, he had heart rhythm abnormalities. On electrocardiogram, his QT interval was 378 ms with a prolonged QT corrected interval of 511 ms, which was "probably related to the patient's severe metabolic acidosis."
Likewise, the girl took five 500-mg tablets of niacin over two days to clear her urine of marijuana and "ecstasy" but wound up in the hospital for nausea, vomiting, dizziness and brief unresponsiveness.
She also had high-anion-gap metabolic acidosis as well as initial hypoglycemia (70 mg/dL) that became hyperglycemia after administration of dextrose (peak 222 mg/dL). However, she did not have elevated hepatic enzymes.
Both demonstrated coagulopathy. The peak prothrombin time was 18.8 seconds for the boy and 23.1 seconds for the girl (normal range 10.3 to 12.8 seconds). The INR peaked at 1.74 on day three for the boy and 3.8 for the girl.
