The SSRIs, although principally targeting serotonin transporter, are complex drugs that might work on other neurotransmitter and receptor systems. It is likely worthwhile to look at the effects of other monoamine and neuropeptide systems on the enzymatic machinery cleaving the amyloid precursor protein.
Is there something in young blood that holds the key to preventing or reversing cognitive decline and/or dementia associated with aging? The answer to that question is the subject of intense recent research. Details here.
Severe alcohol dependence and frequent relapses in this patient prompts his son to produce a durable power of attorney for health care. He demands that the physicians declare his father to lack decision-making capacity. More in this ethics case report.
What treatments are effective for mild chronic depression in older patients? Are there novel antidepressant medications with fewer adverse effects than current treatments? In this podcast, experts report on the latest updates in the evaluation and treatment of depression in older adults.
Our brains can be trained to function better as we age, and it doesn't take the Fountain of Youth to get there. In this podcast, geriatric psychiatrist Helen Lavretsky prescribes strategies to challenge our brains. She notes: "The more we challenge our brain, the more new nerve pathways and circuits we form."
In this podcast, Dr Helen Lavretsky discusses the topic of appropriate diagnosis of mild cognitive impairment. It will be increasingly important to strengthen the definitions of what is “normal” to avoid the “pathologizing” of aging or of any individuals who experience temporary or continuous cognitive impairment.