Although antidepressants are advised only as second-line treatment in patients with bipolar disorder, the matter is complicated by conflicting data surrounding antidepressant use during pregnancy. Read More
The diagnosis of bipolar disorder is typically associated with significant disability and impaired functioning. This article explores the pros and cons of functional and quality-of-life measures. Read More
Dr Lake is in private practice in Monterey, Calif, is on clinical faculty in the department of psychiatry and behavioral sciences at Stanford University Hospital, and is visiting assistant professor of medicine, Arizona Center for Integrative Medicine, The University of Arizona College of Medicine.... More »
Findings of a recent large population survey suggest that 1 in 3 adults in this country (approximately 72 million people) uses 1 or more complementary and alternative medicine (CAM) modalities during any given year.1 Many CAMs are widely regarded as safe on the basis of their established uses in... More »
According to the World Health Organization, by 2020, depression will be second only to heart disease as a cause of disability and premature death in established market economies.1 With unsatisfactory monoamine-based pharmacotherapy and the high comorbidity of medical illnesses in... More »
Everyone is unique at the level of social, cultural, psychological, biological, and possibly "energetic" functioning. By extension, in every person, the complex causes or meanings of symptoms are uniquely determined. The diversity and complexity of factors that contribute to mental illness often... More »
Although there is evidence in the research literature from as far back as 40 years showing that the symptoms of attention-deficit/hyperactivity disorder (ADHD) often persist into adulthood, it has been only in the past decade or so that integrative treatment models designed specifically for adult... More »
More than half of parents treat their child’s ADHD symptoms with vitamins, dietary changes, and expressive therapies—but only a small minority tell their doctor. And roughly 8 out of 10 patients who use complementary and alternative medicine treatments regard them as primary therapy. Listen to Dr Richard Balon discuss his choice for "Top Paper of the Year"—an article on CAM therapies written by Dr James Lake.