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Major Depressive Disorder

Late-life depression is defined in this article as unipolar depressive syndromes that older adults experience, typically around age 60 or older with clinically significant depressive symptoms or minor depression. Details here.

Related content:
New Directions in Psychiatry
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Major Depressive Disorder

The high rate of recurrence of depressive symptoms and ongoing psychosocial challenges point to the need for a longer-term view of the management of adolescents with depressive disorders.

Vitamin D has been hailed as the “sunshine” vitamin with many therapeutic attributes. The authors explore the association between vitamin D deficiency and increased risk of depression.

Dysexecutive syndromes result from damage to the anterior regions of the brain and present as a combination of disinhibition, disorganization, or apathy. More in this CME.

Depression is a frequent psychiatric comorbidity among patients with restless leg syndrome. The case presented here illustrates the importance of evaluating for RLS symptoms in patients with major depressive disorder who complain of insomnia.

"Depression is overwhelming and overpowering, and it crushes its prey." Here: a pediatrician tells of her 40-year battle with severe depression, and offers insights about how to talk with someone who is depressed.

A reexamination of flurothyl infusions holds promise for improved resolution of severe mood disorders, as well as for a greater understanding of the mechanism of their pathophysiology.

When most people think of serious illnesses, they generally have in mind those that can destroy the body, such as heart disease, cancer, and diabetes.

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