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Major Depressive Disorder

An Adequate Dose

Clinicians are often faulted for failing to give an antidepressant medication at a high enough dose. What is "high enough"?

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Tai Chi for Depression?

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Major Depressive Disorder

Are antidepressants safer and more effective in type II vs type I bipolar disorder? What factors predict use of benzodiazepines in patients with bipolar disorder? Insights here.

Striking findings on the relationship between stress and depression.

Experts summarize data on the role of inflammation in psychiatric disorders, emphasizing that evidence for anti-inflammatory treatment for mood disorders is limited, and mixed.

Simply telling patients “we don’t know how ECT works” neglects our abundant knowledge of what this treatment does. The authors review biological actions of ECT and discuss future directions for research.

Is negative perceptual bias a trait of persons prone to major depressive disorder or a modifiable symptom of the current depressive state?

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Recent studies find powerful biological changes associated with mind-body interventions comparable to those associated with conventional antidepressants or psychotherapies.

Over the past 10 years, a growing literature has documented the significantly increased rates of stress, burnout, depression, and suicidal ideation in medical students.


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