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Home » Mania

Psychiatric Times. Vol. 21 No. 12
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Hypersexuality in Children With Mania: Differential Diagnosis and Clinical Presentation

By Barbara Geller, M.D., and Rebecca Tillman, M.S.
| October 1, 2004
Dr. Geller is a professor of psychiatry at Washington University in St. Louis. Ms. Tillman is a research statistical data analyst at Washington University in St. Louis.

Characteristics and Assessment of Hypersexuality

Unlike adults with mania, multiple marriages and overt acts of sexual promiscuity will not be present in children, as they are not developmentally appropriate manifestations of hypersexuality. Rather, in children with mania, these symptoms are manifested by flirtatious or sexualized behaviors that are both age- and situation-inappropriate (Geller et al., 2002b). To assess the symptoms of prepubertal mania, including hypersexuality, it is important to separately interview parents about their children and children about themselves (Tillman et al., 2004). In addition, it is useful to observe the children for hypersexual behaviors during the interview. Examples of hypersexual behavior, as seen in children with a comprehensive research diagnosis of mania and in whom abuse and overstimulation were ruled out (Geller et al., 2000; Geller et al., 2002b), include: trying to touch private places on the examiner; rubbing themselves suggestively on table edges; imitating sexy rock stars; and touching themselves in a flirtatious manner or using highly explicit sexual act language. Areas that should be assessed include the types of magazines and movies the child seeks; their use of foul or dirty language out of proportion to peers or siblings; craving sex (in adolescents); and calling toll-free sex hotlines.

The Table compares examples of hypersexual behaviors in children with prepubertal and early adolescent bipolar disorder phenotype (as found in WASH-U-KSADS Assessments) with the behaviors of normal children and adults with BD.

Normative Sexual Behavior in Children

There are several studies of normative sexual behaviors in children of comparable age range to the prepubertal and early adolescent bipolar disorder phenotype group (average=10.9 years, standard deviation=2.6); however, these studies did not include frequencies of the behaviors or whether the behaviors were clinically meaningful (Friedrich et al., 1998, 1992, 1991; Sandnabba et al., 2003; Schoentjes et al., 1999). Because studies of normative sexual behaviors in children did not include frequencies, it is problematic to compare these normative findings with the pathologically impairing hypersexual behaviors that occur persistently and pervasively in prepubertal and early adolescent bipolar disorder phenotype.

Furthermore, in these studies, normative sexual behaviors included items--such as "sleeps during the day" and "plays house" (Sandnabba et al., 2003)--that have uncertain relationships to pathological hypersexuality, which is usually characterized by behaviors that are sufficiently frequent and impairing to warrant clinical attention. For example, hypersexual behaviors exhibited by children with prepubertal and early adolescent bipolar disorder phenotype often resulted in being sent to the school principal or being asked not to attend church (i.e., the behaviors were impairing and led to clinical evaluation) (Geller et al., 2002b).

Child Abuse and Neurological Diagnoses

One of the key problems in evaluating hypersexual behaviors in children is the need to rule out child abuse or overstimulation. Comprehensive histories of home, school, latchkey after-school programs and extracurricular activities are necessary. Included must be multiple sources of independent information such as pediatric records and school reports. Also important is noting types of reported accidents and injuries and whether there are multiple or single caregivers (abusive guardians may frequently switch caretakers or use emergency departments to avoid suspicion). Whether sexual actions preceded the mania symptoms or are only present during mania symptoms is also useful information to obtain.

Temporal lobe epilepsy can present with persistent and pervasive sexual talk or actions, as can certain brain masses. These should be especially considered in children in whom other signs and symptoms of mania are not present and in those for whom there is a negative family history of mood disorders, as children with BD often have dense family histories.

Stimulatory Behaviors in Other Psychiatric Disorders

Specific data comparing sexual and/or stimulatory behaviors across child psychiatric disorders are not available. Clinically, they may be distinguished by looking at the actions. Manic hypersexuality has a flirtatious, cute, funny quality. By contrast, children with pervasive developmental disorders, schizophrenia or tic disorders display behaviors such as rubbing their genital areas (self-stimulation) or stating sexual words--actions that are usually neither flirtatious nor amusing. For example, a 10-year-old boy with hypersexuality told the research nurse (a grandmother) that he "liked older women" and asked her if he could play some music so that they could dance. This child was being inappropriately sexual in an amusing way; people smile when they hear this example. In contrast are grade-school-age children who rubbed and scratched their genital areas repeatedly, sometimes until the area was scabbed; children who repeatedly poked fecal material out of their anal areas; and a 6-year-old child who drew a picture of a naked girl in a cage after the girl did not want to play with him. Children with tics or compulsions may repeatedly put their hands on and off the genital area or have coprolalia. Thus, behaviors can involve the genital area or use of sexual-organ or bathroom-function language without being sexual.

Managing Hypersexuality in Children With Mania

Overall management will vary with the age of the child. The main concerns for adolescents with mania revolve around unprotected sex and the risks of pregnancies and sexually transmitted diseases. Therefore, it is exceedingly important to inquire about sexual behaviors and to intervene as promptly as possible with mood-stabilizing treatments and restrictive environments. For children, one concern is that parents not be accused of abuse when none is present and when the hypersexuality has not yet been seen as part of a manic syndrome. School personnel need to be educated that

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References
1 Craney JL, Geller B (2003), A prepubertal and early adolescent bipolar disorder-I phenotype: review of phenomenology and longitudinal course. Bipolar Disord 5(4):243-256.
2 Friedrich WN, Fisher J, Broughton D et al. (1998), Normative sexual behavior in children: a contemporary sample. Pediatrics 101(4):E9.
3 Friedrich WN, Grambsch P, Broughton D et al. (1991), Normative sexual behavior in children. Pediatrics 88(3):456-464.
4 Friedrich WN, Grambsch P, Damon L et al. (1992), Child Sexual Behavior Inventory: normative and clinical comparisons. Psychol Assess 4(3):303-311.
5 Geller B (2002), Longitudinal and family study validators of a prepubertal and early adolescent bipolar disorder phenotype. Bipolar disorder in children and adolescents. Conference 3-7. Presented at the 41st Annual Meeting of the American College of Neuropsychopharmacology. San Juan, Puerto Rico; Dec. 9.
6 Geller B, Badner JA, Tillman R et al. (2004a), Linkage disequilibrium of the brain-derived neurotrophic factor val66met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype. Am J Psychiatry 161(9):1698-1700.
7 Geller B, Bolhofner K, Craney JL et al. (2000), Psychosocial functioning in a prepubertal and early adolescent bipolar disorder phenotype. J Am Acad Child Adolesc Psychiatry 39 (12):1543-1548.
8 Geller B, Tillman R, Craney JL, Bolhofner K (2004b), Four-year prospective outcome and natural history of mania in children with a prepubertal and early adolescent bipolar disorder phenotype. Arch Gen Psychiatry 61(5):459-467.
9 Geller B, Zimerman B, Williams M et al. (2001), Reliability of the Washington University in St. Louis Kiddie Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS) mania and rapid cycling sections. J Am Acad Child Adolesc Psychiatry 40(4):450-455.
10 Geller B, Zimerman B, Williams M et al. (2002a), DSM-IV mania symptoms in a prepubertal and early adolescent bipolar disorder phenotype compared to attention-deficit hyperactive and normal controls. J Child Adolesc Psychopharmacol 12(1):11-25.
11 Geller B, Zimerman B, Williams M et al. (2002b), Phenomenology of prepubertal and early adolescent bipolar disorder: examples of elated mood, grandiose behaviors, decreased need for sleep, racing thoughts and hypersexuality. J Child Adolesc Psychopharmacol 12(1):3-9.
12 National Institute of Mental Health research roundtable on prepubertal bipolar disorder (2001), J Am Acad Child Adolesc Psychiatry 40(8):871-878.
13 Robins E, Guze SB (1970), Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia. Am J Psychiatry 126(7):983-987.
14 Sandnabba NK, Santtila P, Wannas M, Krook K (2003), Age and gender specific sexual behaviors in children. Child Abuse Negl 27(6):579-605.
15 Schoentjes E, Deboutte D, Friedrich W (1999), Child sexual behavior inventory: a Dutch-speaking normative sample. Pediatrics 104(4 pt 1):885-893.
16 Tillman R, Geller B, Craney JL et al. (2004), Relationship of parent and child informants to prevalence of mania symptoms in children with a prepubertal and early adolescent bipolar disorder phenotype. Am J Psychiatry 161(7):1278-1284.


 
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