1. Which of the following was the first MAOI—referred to as a “psychic energizer”?
C. Phenelzine(Drug information on phenelzine)
D. Selegiline(Drug information on selegiline)
2. Once ECT was shown to be effective for treating depression, the neurobiological cause for depression was crystallized.
3. As a metabolizer of serotonin and norepinephrine(Drug information on norepinephrine), which of the following is most clearly linked to depression?
4. Which of the following is true of an irreversible MAOI?
A. The binding of the MAOI to the enzyme is temporary
B. It inhibits the activity of monoamine oxidase
C. Depending on the MAOI, the half-life of the drug plays an important role in efficacy
5. When MAO is inhibited, tyramine will release ________________; excessive amounts will consequently raise blood pressure.
A. Dopamine(Drug information on dopamine)
C. Epinephrine(Drug information on epinephrine)
6. Which of the following is safe on a low-tyramine diet?
A. Red wine
B. Beer on tap
7. MAOIs have remained in the armamentarium as a first-line treatment for which of the following?
A. Unipolar depression
B. Atypical depression
C. Bipolar depression
8. Patients with refractory depression treated with tranylcypromine should start the restricted diet 1 day before taking the medication and continue the diet for 2 weeks after stopping the medication.