Meet the Columnist
Dr Medina is a developmental molecular biologist and private consultant, with research interests in the genetics of psychiatric disorders. For more about Dr Medina, visit www.brainrules.net.
Modeling Schizophrenia: An In Vitro Model of a Tough Disease
October 6, 2011
This column has always been about the world of molecular mental health research. I revisit the technology in this column, now aimed at one of molecular neuropsychiatry’s most intractable, frustrating lines of research: the molecular/cellular basis of schizophrenia.
Custom-Made Neural Stem Cells
May 4, 2011
In this column, we explore how the judicious use of neural stem cells (NSCs) has led to a research Holy Grail: the creation of research-ready, patient-specific neurons.
The Business of Pleasure and Pain
December 2, 2010
The neuroanatomical linkage that emerges from a normal part of business experience—the reaction to success and also to failure (especially if that failure happens to someone else)—is the focus of this column.
Elegant Knockdowns, DISC1, and Schizophrenia
June 3, 2010
When I was a grad student—back in the Jurassic Era of molecular manipulations—my lab mates and I were all transfixed by the notion of a new technology: knockout animals (KOAs). This was because of its promise to solve a vexing problem.
The Epigenetics of Stress
April 7, 2010
Overly sensitive, aversive reactions to stress seem to run in families. The literature abounds with reports of relatives in these populations predisposed to depression, anxiety, and even suicide. Some family members present with glucocorticoid levels notched abnormally high, and in curiously deregulated concentrations. Behaviorally, they seem to exist at a permanent state of high alert.
The Genetics of Temperament—An Update
March 10, 2010
There are a lot of temperamental Jerome Kagan moments in my friend’s household—an observation that will require this entire column to explain. What exactly is a temperamental moment? And who exactly is Jerome Kagan?
FROM PHYSICIANS PRACTICE
Five Steps to Improving Patient Access Judy Capko,
May 21, 2013
Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.
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