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Signals * promising developments for neurology
A team of neuroscientists from Purdue University and Nagoya University in Nagoya, Japan, has identified acrolein as a key neurotoxin in the neurodegenerative process that follows traumatic spinal cord injury. Acrolein, a toxic industrial by-product, naturally occurs in the body in negligible quantities as free radical molecules. However, it can quickly accrue to toxic levels in response to trauma, stress, or exposure to environmental carcinogens. Carriage More »
Neurologists Now: Computerized, a Bit Older, and a Few More Women

general neurology

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Neurology Newsfeature Neurology Subspecialization Takes a Step Forward
Subspecialization within the practice of neurology is now reality with the recent approvals of subspecialty designations for neuromuscular pathology, headache medicine, and neuro-oncology. The American Academy of Neurology (AAN) Committee on Neuromuscular Pathology sponsored the neuromuscular pathology membership application. Two associations--the AAN Headache and Facial Pain Section and the American Headache Society--sponsored the headache medicine application. More »
Signals * promising developments for neurology

An estimated 18,500 cases of primary cancer of the brain and CNS will be diagnosed this year, according to the American Cancer Society (Cancer Facts and Figures 2005;

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Clinical News & Knowledge: Neurology
Confabulation: A Bridge Between Neurology and Psychiatry?
Mr A is a 73-year-old resident of a nursing home, where the irate aides describe him as “a liar and a troublemaker.” Mr A had been a successful and well-liked businessman until 2 years ago, when he sustained a stroke secondary to a ruptured aneurysm of the anterior communicating artery. Prominent memory deficits ensued. Mr A also became irritable, verbally abusive, and “hard to manage.” Staff also complained that Mr A “made up stories about the staff, just to get us in trouble . . . like, that... More »
News from the 59th Annual Meeting of the American Academy of Neurology, Boston, April 28 - May 5, 2007
AC-1202 Improves Cognition in APOE*E4-Negative Patients with AD. A medium chain triglyceride that converts to ketone bodies and counteracts reduced glucose metabolism improves cognitive scores in patients with mild to moderate Alzheimer disease (AD) who do not have the e4 allele of the apolipoprotein E (APOE*E4) gene. More »
News From the 59th Annual Meeting of the American Academy of Neurology, Boston, April 28 - May 5, 2007
Personality Traits Early Clue to Distinguishing LBD From AD. Lewy body dementia (LBD) is often difficult to distinguish from Alzheimer disease (AD) but subtleties in symptoms provide clues to the differential diagnosis. More »
The Year in Neurology
BOSTON -- Clinical and research developments in neurology in 2006 seemed to be as much about prevention as treatment. More »
AAN Releases New Clinical Recommendations About Stroke and Epilepsy
Two new recommendation papers--one on the use of serum prolactin (PRL) in the differential diagnosis of epileptiform seizures and the other on use of carotid endarterectomy (CE) in stroke prevention--were released this past September by subcommittees of the American Academy of Neurology (AAN). More »
Signals * promising developments for neurology

Malformed, reactive astrocytes (blue) interacting with neurons (orange/red) in a human subject whose temporal lobe ultimately was removed because the epilepsy did not respond to pharmacotherapy. Reactive astrocytes are responsible for inappropriate glutamate release, which in turn triggers epileptiform seizures. Image courtesy of Maiken Nedergaard, MD.
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