A thoughtful and deliberate differential diagnosis of possible medical and toxic causes of psychosis is necessary to avoid the mistaken attribution to a psychiatric disorder. A history and physical examination with an emphasis on the neurological and cognitive parts are the cornerstones for the initial approach to psychosis. Taking into account that psychosis can arise from a general medical condition, what of the choices below should clinicians suspect if a patient presents with symptoms of confusion, episodic violence, and catatonia? Take the quiz to test your knowledge.

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