In schizophrenia therapy, perphenazine can play in combating symptoms and in preventing relapse, though it can be associated with metabolic side effects.
Perphenazine was used in the CATIE study. Here, Dr. Peter Buckley addresses:
• The current role of perphenazine in the management of schizophrenia.
• The drug’s association with weight gain.
• The metabolic side effect profile of perphenazine.