The authors evaluate the effects of nicotine and cannabis on neurocognitive function in individuals with schizophrenia and review potential pharmacological treatment strategies. More here.


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More evidence supports the glutamate hypothesis of schizophrenia. Inflammation may be involved

Many patients report that smoking helps them with their stress and psychological disturbances. However, smoking may actually worsen some of these symptoms. When is the right time for your patients to quit?

A debate about research claiming benefits for dose reduction and discontinuation of antipsychotics, and strategies for reducing readmissions.

There is renewed interest and enthusiasm for the potential pathophysiological role of inflammation and immune dysfunction in patients with schizophrenia, with evidence for abnormalities in the blood, CSF, and CNS.

Psychosis is one of the key dimensions of schizophrenia, bipolar disorder, and psychotic depression. Clinicians are familiar with patients whose psychosis improves dramatically with antipsychotic treatment; however, these patients may be left with cognitive impairment, negative mood symptoms, or suicidal symptoms, as well as impaired work and social functioning.

Catatonia—a syndrome of disturbed motor, mood, and systemic signs (eg, rigidity, immobility, mutism, staring, posturing, waxy flexibility, echopraxia, echolalia, and stereotypies)—has led to the clarification of its appropriate treatment.


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