Chronobiology—the science of daily (circadian), monthly, tidal, and seasonal rhythms—has undergone exponential growth in the past decade, with major discoveries at the molecular and neuroanatomic level.
Most patients with psychiatric diagnoses present with sleep disturbances that can have as great an impact on health-related quality of life as the mental illness itself. Here, tips on treatment and chronotherapeutic applications for major depression and other disorders.
What is sleep normally and what are the primary factors that regulate sleep? Understanding that the primary factors that regulate the sleep wake cycle are homeostatic and circadian will help clinicians assess sleep problems in patients.