Cannabis contains many different compounds. Based on the current evidence, how does cannabis affect psychosis?
The correct answer is C.
When discussing the medicinal use of cannabis, it is important to distinguish CBD, with its potential beneficial effects, from THC, with its controversial adverse effects, especially on individuals with psychotic disorders.
With more than 100 types of cannabinoids, cannabis is a complex plant. Its main psychoactive compound is Δ-9- tetrahydrocannabinol (THC), which activates cannabinoid receptors to produce its psychoactive effects of “feeling high.”
Another cannabinoid, cannabidiol (CBD) does not bind to cannabinoid receptors and has shown different, sometimes counteractive, effects.
The potential beneficial effects of CBD on cognition in patients with schizophrenia have critical importance, since cognitive deficits are common in schizophrenia (up to 75%-85% of patients), usually precede other symptoms, and respond minimally to the available pharmacological treatments.
For more on this topic, see Cannabidiol as an Adjunctive Treatment for Schizophrenia, on which this quiz is based.