SPOTLIGHT -
The Clozapine-Infection Connection
Monitoring patients for 5 key changes can help avert drug toxicity.
Mortality Risk After Discharge From Psychiatric Care
Which patients are at greatest risk for premature death following discharge?
Promising New Option for Treatment of Tardive Dyskinesia
The results of a phase 3 trial demonstrated significant benefit over placebo.
Impaired Glucose Homeostasis in First-Episode Schizophrenia
Recent findings suggest metabolic abnormalities may be independent of the effects of antipsychotics.
How Best to Make the Switch to Clozapine
What’s the optimal approach for patients with treatment-resistant schizophrenia?
Ultrahigh-Risk Psychosis: Do Things Come in (Omega)-3s?
Can dietary supplementation decrease the risk of transition to psychosis?
Antipsychotic Augmentation vs Monotherapy in Schizophrenia
To augment or not to augment? That is the question.
Antipsychotics and Breast Cancer Risk
Are antipsychotics associated with an increased risk of breast cancer?
Adjunctive Metformin for Patients With Schizophrenia
A recent meta-analysis shows this agent is useful in the prevention and treatment of antipsychotic-induced weight gain.
Health Technology for Relapse Prevention in Schizophrenia
A “high-tech” approach to relapse prevention in patients with schizophrenia.
Adjunctive Topiramate in People With Schizophrenia
A recent meta-analysis shows this adjunctive agent reduces residual symptoms of psychopathology as well as body weight.
Schizophrenia Risk From 8 to 18
Is inflammation a cause or consequence of illness in schizophrenia?
The Heavy Economic Burden of Schizophrenia
It’s not health care expenses that are driving up costs.
Schizophrenia’s Lethal Infection
Are you aware of this newly identified risk factor for suicide?
Adjunctive Raloxifene for Women With Schizophrenia
This hormone-based therapy shows promise for older women with refractory symptoms.
Aerobic Exercise and Cognition in People With Schizophrenia
What should you tell your patients with schizophrenia about exercise?
Which Psychotropics Up Risk of Death?
Insights from the first study of mortality and cumulative psychotropic exposure in schizophrenia.
When Mom Smokes, Does Schizophrenia Follow?
New insights from a large study that relied on objective biomarkers.
The Perilous Journey of First-Episode Psychosis
What is the risk of symptom recurrence after antipsychotic discontinuation in first-episode psychosis?
DNA Methylation in Schizophrenia
What role does DNA methylation play in schizophrenia?
A Promising Approach to Improve Cognition
Details of a randomized trial of an alpha-7 nicotinic receptor agonist in schizophrenia.
Antipsychotics in Treatment-Resistant Schizophrenia
Is clozapine still the gold standard for treatment-resistant schizophrenia?
Reproductive Safety of Second-Generation Antipsychotics
Do atypical antipsychotics increase the risk of major malformations among exposed infants?
Novel Insights Into the Causes of Schizophrenia: Part 2
The identification of a genetic risk factor has shed light on the underlying neurobiology of the disorder.
Novel Insights Into the Causes of Schizophrenia: Part 1
Groundbreaking work by a Harvard team represents a bold step in our journey toward understanding schizophrenia.
Biomarkers Delineate 3 Distinct Psychosis Biotypes
Brain-based biomarkers identify more biologically homogeneous categories of psychosis than do clinical diagnoses.
Antipsychotic Rechallenge After an Adverse Event
Are you up-to-date on the risk of recurrent pneumonia in patients with schizophrenia when an antipsychotic is reintroduced?
Adjunctive Monoclonal Antibody Immunotherapy in Schizophrenia
New evidence-coupled with advances in molecular biology-has afforded an unparalleled opportunity to move toward identifying potential new treatments for schizophrenia.
Neuroinflammation Marker May Foretell Psychosis
Neuroinflammation may be a culprit in the development of psychosis. What are the clinical implications?
Severe Mental Illness Ups Risk of Death After Infection
How targeted interventions may reduce the burden of premature mortality among patients with schizophrenia and other psychiatric disorders.