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Major Depressive Disorder

Cautious Optimism

Is St. John’s wort an appropriate treatment option? ©ScisettiAlfio/Shutterstock

Related content: Depression Research Update, November 2016

Major Depressive Disorder

Recent studies examine placebo responses to antidepressants, the effect of SSRIs on sleep in the elderly, and the best time of day for psychotherapy sessions.

Two recent clinical trials of opioid medication for depression and suicidality highlight the role of brain opioid systems in depression.

Three new studies help predict which patients with depression may not respond to pharmacotherapy and which women may become depressed during menopause.

Among patients with treatment-resistant MDD, transcranial magnetic stimulation wins the popular vote.


Psychiatrists are playing an ever-increasing role in the evaluation and care of organ transplant candidates and living organ donors—before and after transplant.


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