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Psychopharmacology

An Ounce of Prevention

A game plan for prevention of antidepressant adverse effects. ©Kubais/Shutterstock

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MDD: Predictors and Protectors

Psychopharmacology

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This year we asked about the best and worst things relating to our field. As always, we received a diverse group of responses.

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This article focuses on treatment resistance to medications in adult male and non-pregnant adult female outpatients with any type of DSM-5 diagnosed bipolar disorder.

FIGURE 1

While treatment of bipolar disorder challenging , the notion that it is treatment resistant is contradicted by longitudinal and treatment research that indicates high rates of remission over time, moderate rates of recovery, and significant response to structured treatments tailored to symptoms.

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Trauma-focused cognitive-behavioral therapy, pharmacotherapy, and combinations thereof. Expert guidance here.

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This Special Report on treatment resistance provides expert guidance on how to treat patients who are still unresponsive after multiple unsuccessful attempts at intervention for some common mental disorders.

Recommendations from an international panel of experts on the management of MDD.

Treatment nonadherence in psychiatric patients contributes to increased suicide rates, illness exacerbation, hospitalization, and mortality. This Special Report countdown highlights the psychiatrist’s role in addressing barriers to treatment in a number of scenarios.

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