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Psychopharmacology

Psychopharmacology

What to do once treatment-resistant depression is established based on risk factors and exclusion of other conditions? Insights here—and a treatment algorithm.

Because cognitive and negative symptoms have the greatest impact on overall recovery, interdisciplinary strategies that target these symptoms are necessary. This article offers details.

The discovery that a single IV infusion of low-dose (subanesthetic) ketamine exerts rapid antidepressant effects constitutes an expansion in our understanding of the neurobiology of depression and provides new avenues for drug development.

To combat opiate abuse and its dire consequences, drug makers have developed a number of strategies--which are detailed here.

Glutamatergic models have led to greater understanding of the causes of social and occupational disability in schizophrenia, and thus have provided new targets for remediation and compensation strategies. Details here.

Here's a fascinating study of consumer attitudes towards doctors among patients receiving antidepressants. The conclusions help us understand what goes wrong in the doctor-patient relationship and suggest steps needed to fix it.

How can we get even better at customizing treatment for our patients and thereby achieve improved outcomes? How do we avoid becoming relegated to mere brokers of psychopharmacologic commodities? A few thoughts in this brief communication.

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