SPOTLIGHT -
August 28th 2025
Care partners for patients with schizophrenia can greatly benefit from psychoeducation provided by clinicians.
August 27th 2025
BioXcel Therapeutics reveals promising phase 3 results from the SERENITY trial, paving the way for potential at-home treatment of agitation in bipolar disorder and schizophrenia.
Dive into the forms of assessment for cognitive dysfunction in relation to the diagnosis and treatment of schizophrenia.
August 22nd 2025
BioXcel Therapeutics advances BXCL501 for at-home treatment of agitation in bipolar disorders and schizophrenia, aiming for FDA approval by 2026.
August 19th 2025
Risk Factors for Catatonia Relapse in Psychotic and Affective Disorders
Nearly half of catatonia patients relapse within two years, highlighting the need for effective long-term management strategies and potential benefits of antipsychotics.
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BXCL501 for Agitation Associated With Bipolar Disorders or Schizophrenia: Positive Pre-sNDA Meeting With FDA
BioXcel Therapeutics advances BXCL501 for outpatient treatment of agitation in bipolar disorder and schizophrenia, receiving positive FDA feedback in its pre-sNDA meeting discussion.
Preliminary Report on Chatbot Iatrogenic Dangers
AI chatbots pose significant mental health risks, often exacerbating issues like suicide, self-harm, and delusions, highlighting urgent regulatory needs.
Study Identifies Critical Components of Early Psychosis Intervention
UK study of "active ingredients" in early psychosis intervention is applicable to US programs, according to the codirector of Stanford's INSPIRE Clinic.
Recent Updates in Psychopharmacology: Insights in Schizophrenia, ADHD, and Treatment-Resistant Depression
Stay updated on key psychopharmacology developments, including new treatments for schizophrenia and breakthroughs in depression therapy.
Investigational Prescription Digital Therapeutic CT-155 for Negative Symptoms of Schizophrenia Meets Primary Study End Point
Boehringer Ingelheim and Click Therapeutics achieve breakthrough results in treating negative schizophrenia symptoms with investigational prescription digital therapeutic CT-155.
Levels, Labs, and Lessons
Serum drug levels provide crucial insights for optimizing psychiatric treatment, enhancing patient outcomes in cases of schizophrenia and OCD.
In Summer, Always Ask
Extreme heat poses serious health risks, especially for vulnerable populations. Learn essential tips to help patients stay safe during heat waves and protect their well-being.
Metabolic Health in Schizophrenia: Toward Nutritional and Metabolism-Based Strategies in Psychiatry
Learn more about effective strategies for managing obesity and metabolic dysfunction in schizophrenia, focusing on dietary interventions and pharmacological treatments.
Potential Label Expansion for Igalmi: Pre-Supplemental New Drug Application Meeting Package Submitted
BioXcel Therapeutics has submitted an pre-sNDA meeting package for Igalmi's outpatient use, aiming to enhance treatment options for agitation in bipolar disorders and schizophrenia.
Long-Term Antipsychotic Use May Be Linked to Increased Breast Cancer Risk in Women With Schizophrenia
Women with schizophrenia face increased breast cancer risks linked to long-term prolactin-raising antipsychotic use, highlighting the need for regular screenings and tailored treatment strategies.
Clinician Tips in Prescribing New Xanomeline-Trospium for Schizophrenia
Clinicians explore the potential of xanomeline-trospium for schizophrenia, emphasizing cautious evaluation and management of side effects for optimal patient outcomes.
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Robust Efficacy and Decreased Side Effects with New Muscarinic Agent for Treating Schizophrenia
Discover groundbreaking schizophrenia treatments using the muscarinic pathway, offering efficacy without common side effects of traditional antipsychotics.
Toward a Muscarinic Agent Solution for the Presynaptic Dopamine Problem in Schizophrenia
Discover groundbreaking schizophrenia treatment with xanomeline-trospium, targeting cholinergic pathways for improved symptoms and fewer side effects.
Spotlight on Schizophrenia Data: Insights From Recent Conferences
Discover promising new treatments for schizophrenia, including NBI-1117568 and CPL’36, showcasing significant symptom improvements and safety profiles.
sNDA Submitted: Lumateperone for the Prevention of Relapse in Schizophrenia
Johnson & Johnson has submitted an sNDA for Caplyta, showcasing significant relapse prevention in schizophrenia.
Transformation 2.0: The GLP-1 RAs as Psychiatric Medications?
GLP-1 receptor agonists emerge as potential game-changers in psychiatric treatment, targeting mental disorders and improving cognitive function.
Impulse Control Disorders, Psychosis, and Cognitive Impairment in Parkinson Disease
In this CME article, learn more about the complexities of neuropsychiatric symptoms in Parkinson disease, including psychosis and cognitive impairment, and effective treatment strategies.
Marking Progress, Promise of Prescription Digital Therapeutics for Mental Health: Interview with Shaheen Lakhan, MD, PhD
Innovative digital therapeutics like CT-155 are transforming mental health treatment, targeting negative symptoms of schizophrenia and enhancing depression care. Check out this conversation with Shaheen Lakhan, MD, PhD.
Prodromal Symptoms of Schizophrenia: Understanding and Addressing Challenges
It is critical to recognize the early signs of schizophrenia and provide timely intervention to prevent full-blown psychosis in adolescents.
FDA Officially Eliminates Clozapine REMS
The FDA's removal of clozapine REMS enhances access to treatment, while new educational initiatives empower clinicians to improve patient care.
Tardive Dyskinesia: Treat Functional Impairment, Not the AIMS Score
Learn more about how to best assess and treat tardive dyskinesia.
Open Label Phase 3 Study of Brilaroxazine for Schizophrenia Shows Efficacy, Tolerability
The RECOVER open label trial demonstrated positive results for brilaroxazine for schizophrenia.
Treatment Comparison: Somnolence/Sedation With Dopamine Partial Agonists vs D2 Receptor Antagonists
Recent research reveals dopamine partial agonists significantly reduce somnolence in major depressive disorder and schizophrenia compared with D2 receptor antagonists.
Positive Phase 2 Results on NBI-1117568 for Schizophrenia Presented at 2025 ASCP Annual Meeting
Neurocrine Biosciences reveals promising phase 2 results for NBI-1117568, a novel treatment for schizophrenia, showing significant symptom improvement over placebo.
The Enduring Impact of Early Adversity on Psychosis Risk
Learn more about the critical link between early adversity and psychosis, and the need for targeted interventions and preventive measures.
From a Dysfunctional Neuromodulator to a Dysfunctional Circuit
Explore the complex role of dopamine in schizophrenia, its impact on symptoms, and potential therapeutic advancements.
Coordinated Specialty Care: Paving the Way for Psychosis Recovery
Early intervention in schizophrenia enhances recovery, reduces symptoms, and improves quality of life through coordinated specialty care programs across the US.
Major Changes in the Treatment of Schizophrenia: A Long Time in the Making
In this Special Report, explore groundbreaking insights on schizophrenia treatment, early intervention strategies, and the impact of childhood trauma on psychosis.
Use of Plasma Levels of Antipsychotics: A Conversation With Jonathan M. Meyer, MD, DLFAPA
Antipsychotic plasma levels play a critical role of in treatment decisions. Learn more in this conversation from the 2025 APA Annual Meeting.