Enhancing Patients' Motivation and Empowerment: A Resident’s Perspective
March 22nd 2024Empowerment has a significant correlation with patients’ overall mental and physical well-being, and has been central to the shift in conceptual framework of mental illness recovery towards a focus on resilience, strength, and control over one’s life.
Augmentation Strategies for Treatment-Resistant Depression
March 19th 2024Given that two-thirds of patients treated for a major depressive episode will fail to achieve remission of symptoms after 2 or more treatment trials of first-line antidepressants, the probability of remission will further decrease with subsequent medication trials. Treatment strategies for patients with TRD include augmentation, where a medication is added to a current antidepressant versus switching to a different antidepressant.
Mild Cognitive Impairment and Serotonin System Degeneration
March 14th 2024“If we can show that serotonin loss over time is directly involved in the transition from mild cognitive impairment to Alzheimer disease, recently developed antidepressant medications may be an effective way to improve memory deficits and depressive symptoms and, thus, may be a powerful way forward to slow disease progression.”