Topics:

Depression

Persistent Depressive Disorder

An update on the diagnosis, causation, and treatment of chronic depressive problems.

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Depression

Chronobiology—the science of daily (circadian), monthly, tidal, and seasonal rhythms—has undergone exponential growth in the past decade, with major discoveries at the molecular and neuroanatomic level.

Given the greater frequency of depression than manic episodes in bipolar disorder, what clues indicate bipolar disorder rather than unipolar depression?

The “story behind the story” is not the over-prescription of antidepressants—though it happens—but the under-availability of optimal treatment.

Persons with epilepsy have a higher prevalence of comorbid conditions -- psychiatric disorders in particular -- than the general population. Here: a look at the most common comorbidities and a discussion of the clinical implications.

Here: an update on the diagnosis, causation, and treatment of chronic depressive problems. The focus is on the recently introduced diagnostic category of persistent depressive disorder.

Here: the history of psychotic depression for the Study of the Pharmacotherapy of Psychotic Depression (STOP-PD), a summary its epidemiology, significance, diagnostic complexity, and treatment, as well as case vignettes.

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