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Psychiatric Epigenetics: A Key to the Molecular Basis of and Therapy for Psychiatric DisordersThe major challenges for epigenetic therapies are target specificity of the drugs-an issue that is also true for most of the currently used drugs in medicine, especially in psychiatry.
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Dementia: A Focused ReviewThis article reviews the differences between dementia types and future directions.
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Psychotic Disorders in DSM-5: Clinical Implications of Revisions From DSM-IVThe authors discuss the clinical implications of the changes in the DSM-5 section on schizophrenia spectrum and other psychotic disorders.
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Sleep Hygiene: Tips on Getting a Restful Night's SleepConcerned about daylight savings time? This patient handout offers tips for getting a good night's sleep.
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Why Clinicians Should Be Excited About Austedo XRRakesh Jain, MD, shares more about the recent approval of Austedo XR for the treatment of tardive dyskinesia and Huntington disease chorea control.
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A Guide to Interventions for Pediatric Seizure DisordersThe Workforce Task Force of the American Academy of Neurology projects that the number of pediatric neurologists will be 20% below demand, at least through the year 2020
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Treatment of Sudden, Intense Rage Reactivity After Minor Head InjuryPropranolol therapy at a relatively low dose can cause anger and rage behaviors to subside in some patients. This case describes a man with Down syndrome who, after an accident, sustained minor brain trauma. Subsequently, he regressed to a rage state he had experienced when he was younger.
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Implications for Treatment and Prognosis of Borderline and Substance Use DisordersBorderline personality disorder (BPD) and substance use disorder (SUD) often co-occur. Comorbid BPD and SUD is related to a variety of severe adverse outcomes.
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Mini Quiz: Treatment for PTSDWhich medications have consistently replicated randomized placebo-controlled trial evidence of efficacy in treating symptoms that are unresponsive to sertraline or paroxetine? Take the quiz and learn more.
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Discrediting the Expert Witness on Account of BiasThe issue of psychiatrists serving as forensic expert witnesses has long been controversial. What are the rules for serving as an expert witness, and what is expected of a psychiatrist who serves as an expert witness?
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SPIRIT (Social Psychiatry Interested in Recovery from International Trauma) Voices Some Current ConcernsAll these events that occurred over the weekend bear social psychiatric weight.
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Cognitive Difficulties Associated With Mental DisordersAny person who once “drew a blank” during an exam is familiar with the horrors of cognitive difficulties: that terrible moment is for most of us so rare that it remains a traumatic memory for years to come. Imagine those who suffer from protracted cognitive difficulties.
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Can We Predict Response to Antidepressants?In this article, we use the example of major depressive disorder (MDD) to review research efforts to identify predictors of treatment response, both to antidepressant medications and to psychotherapy. We describe the promises and limitations of this research, with some emphasis on brain imaging studies, and then discuss how this work may be integrated into clinical practice in the future.
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Will Choline Supplementation During Pregnancy Play a Role in Schizophrenia Prevention?Schizophrenia has long been considered a neurodevelopmental disorder in which onset of diagnostic symptoms in late adolescence or adulthood is the end result of a decades-long interaction between genes and environment that begins in the womb.
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Insights Into Depression and Anxiety: Overview of the Anxiety DisordersInsights Into Depression and Anxiety: Overview of the Anxiety Disorders
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Diagnosis and Treatment of Late-Life DepressionClinicians will likely encounter increasing numbers of older adults with late-life depression. Advances in our understanding of the neurobiology can help inform diagnosis and prognosis.
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E-mail, Intimacy, and Concierge MedicineE-mail is not for every physician. Legal concerns and HIPAA compliance are perceived barriers to using e-mail. They are excuses. There are, however, practical reasons that prevent most docs from considering e-mail.
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Autism Spectrum Disorders, Down Syndrome, and 22q Deletion SyndromeWith aging, a multitude of medical conditions can occur and/or existing conditions can be exacerbated, contributing causally to or amplifying neuropsychiatric comorbidities.
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The Dementias: Neuropsychiatric Syndromes of the 21st CenturyIn the new century, the dementias will probably become 1 of the 2 or 3 dominant behavioral health problems in the United States. This article provides an overview of the major clinical features of these cognitive loss syndromes and emphasizes the perspective of the practicing psychiatrist.
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The Importance of Evolutionary Psychiatry Explored at Annual MeetingLeveraging evolutionary psychiatry may help clinicians and patients alike.
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Mini Quiz: Social PhobiasWhen treating social phobias, the addition of D-cycloserine has been noted to enhance the response to behavior therapy. How does D-cycloserine promote fear extinction?
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People Who Hoard AnimalsThe existing literature on the hoarding of animals by human beings has been written by officials of the Humane Society of the United States and animal shelter operators. Only one case series appears in medical or psychological literature.
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The Hoarding of Animals: An UpdateThe authors provide information about the human-animal bond that may provide a starting point for understanding the development of animal-hoarding disorder.
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Symposium on Psychology and National Security at the Italian EmbassyThe Embassy of Italy in Washington, DC recently hosted the first of 2 workshops on “Leaders and Terrorists: Psychological Perspectives on National Security.”
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Movement Disturbances Associated With SSRIsThe SSRIs have become the most widely prescribed antidepressants in the United States. With this increased use has come more information on adverse events associated with their use, such as sexual dysfunction. However, movement disturbances associated with SSRI use can adversely impact treatment. This article explains the pathology of movement disorders and describes confounding variables such as other medications, pre-existing neurological insults and the nature of case reviews. Those at risk include the elderly, patients taking neuroleptics and those exposed to high levels of SSRIs.
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Flakka: A Deadly HighThe abuse of this dangerous designer drug that can be purchased online is rapidly on the rise in the US.
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Unique Challenges and Joys of Rural Small-Town Outpatient PsychiatryWhen you have a strong team, you can provide quality mental health care and have an immensely satisfying career-even in the middle of a cornfield.
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The DSM-5 Cultural Formulation Interview and the Evolution of Cultural Assessment in PsychiatryThis evidence-based tool is composed of a series of questionnaires that assist clinicians in making person-centered cultural assessments to inform diagnosis and treatment planning.
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Comorbid Clinical and Personality Disorders: The Risk of SuicidePersonality disorders are arguably the most challenging for psychiatrists because they are difficult to diagnose and frequently coexist with psychotic, affective, and anxiety disorders.
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Macho, Bravado, and Eating Disorders in Men: Special Issues in Diagnosis and TreatmentEating disorders are still thought of as a “female problem.” But 25% of those with anorexia and 36% of those with bulimia are males.
