Neuropsychiatry

Disruptions to cognitive control, as well as to emotional processes, are implicated in a wide range of psychiatric disorders.

Cognitive symptoms affect between 85% and 94% of patients with major depressive disorder. Despite this prevalence, cognitive dysfunction often remains undertreated and inadequately addressed in routine clinical practice.

Given that individual differences exist regarding the effects of brain injury and gaps persist in the treatment continuum, challenges arise in treating individuals with acquired brain injury. Addressing these challenges can improve patient outcomes.

A new trial is testing a first-of-its-kind stem cell therapy for Parkinson disease, using a patient’s own reprogrammed cells to restore lost dopamine function.

Neurocrine Biosciences has initiated a phase 1 clinical study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of NBI-1140675 for certain neurological and neuropsychiatric conditions, such as tardive dyskinesia.

Frontal lobe syndrome can present with a range of perseverative, disinhibited, overactive behaviors that do not meet traditional dementia/neurocognitive disorder criteria. Learn more here.

Because diagnosis and management of concussions remain challenging, reliable biomarkers can improve effective intervention.

The lates update in lecanemab’s journey: the FDA has accepted the BLA for lecanemab-irmb subcutaneous autoinjector for weekly maintenance dosing.

The FDA grants Breakthrough Device Designation to Spear Bio’s pTau 217 blood test for Alzheimer disease.

Learn more about the latest research on different approaches to treatments for major depressive disorder (MDD).

Check out these examples of neuroplasticity.

How can we optimize and expand our knowledge of neuroplasticity?

Psychiatric Times: Supporting clinicians, promoting conversations, and improving patient care over the past 40 years.

Who would be the optimal candidate to receive focused ultrasound to treat obsessive-compulsive disorder?

Brain injury was recently recognized as a chronic health condition.

A new study shows that rTMS has moderate therapeutic effects on OCD severity.

In this CME article, learn more about the efficacy and tolerability of brexpiprazole for the treatment of agitation among individuals with Alzheimer disease dementia.

It is important to raise awareness about alpha-gal syndrome and the risks of tick exposure, and to provide resources to medical providers treating patients with this condition.

A traumatic brain injury sustained earlier in adult life is likely to interact with normal aging processes. Learn more here.

Neurosyphilis may occur during any stage of syphilis. Learn more about this diagnosis via case study example here.

Will this help my sleep and mood? Researchers investigated the effects of noninvasive neurostimulation on sleep quality and depressive symptoms in patients with major depressive disorder in a meta-analysis of randomized controlled trials.

Abbott has initiated the TRANSCEND study to evaluate the use of deep brain stimulation to manage treatment-resistant depression.

The impact of plastics on health is an area of increasing concern.

In this guest column, learn more about intensity, repetition, consistency, and integrity in rehabilitating neurological injury.

Studies report an increased risk for suicidal thoughts, suicide attempts, and even death by suicide following brain injury.

The behavioral and psychological symptoms of dementia contribute significantly to the greater rates morbidity and mortality among those with dementia.

Research shows an increased risk for suicidal thoughts, suicide attempts, and even death by suicide following brain injury.

Do physical health conditions in childhood affect ADHD symptoms at age 17 years? Researchers investigated these associations in a large cohort study.