Eric J. Nestler, MD, PhD

Eric Nestler, MD, PhD, reflects on his research and new role as dean of the Icahn School of Medicine.

Certain aspects of depression result from maladaptive stress-induced changes in reward circuits of the brain.

While progress in identifying the specific genetic variations that help determine an individual's vulnerability to addiction has been slow, a great deal has been uncovered about delineating the role that numerous genes and their protein products play in mediating the development of addiction.