Articles by Leonardo Tondo, MD, MSc
“Switching” of Mood From Depression to Mania With Antidepressants
ByRoss J. Baldessarini, MD, PhD,Gianni L. Faedda, MD,Emanuela Offidani, PhD,Gustavo H. Vázquez, MD, PhD,Ciro Marangoni, MD,Giulia Serra, MD,Leonardo Tondo, MD, MSc Mood switching is not uncommon and it is much more prevalent in depressed juveniles than in depressed adults, and there is a large apparent excess of antidepressant-associated switching over reported spontaneous diagnostic changes to bipolar disorder. Details here.
Major mood disorders have been associated with increased suicidal behavior. This is especially true in patients with a mixed, manic-depressive, or dysphoric-agitated state.
