Can Diet Treat Depression?

Sep 15, 2017

Although supported by basic science, it’s still a sea change to think that diet can treat depression. A new clinical trial puts that idea to the test.

View the slides in PDF format.REFERENCES1. Jacka FN, O’Neil A, Opie R, et al. A randomised controlled trial of dietary improvement for adults with major depression (the 'SMILES' trial). BMC Med. 2017;15:23.2. Faraone SV, Biederman J, Spencer TJ, et al. Comparing the efficacy of medications for ADHD using meta-analysis. MedGenMed. 2006;8:4.3. Turner EH, Rosenthal R. Efficacy of antidepressants. BMJ. 2008;336:516-517.4. Opie RS, O’Neil A, Jacka FN, et al. A modified Mediterranean dietary intervention for adults with major depression: dietary protocol and feasibility data from the SMILES trial. Nutr Neurosci. 2017;19:1-15.5. Chang SC, Cassidy A, Willett WC, et al. Dietary flavonoid intake and risk of incident depression in midlife and older women. Am J Clin Nutr. 2016;104:704-714.6. Dong X, Yang C, Cao S, et al. Tea consumption and the risk of depression: a meta-analysis of observational studies. Aust N Z J Psychiatry. 2015;49:334-345.7. Grassi D, Socci V, Tempesta D, et al. Flavanol-rich chocolate acutely improves arterial function and working memory performance counteracting the effects of sleep deprivation in healthy individuals. J Hypertens. 2016;34:1298-1308.8. Bowtell JL, Aboo-Bakkar Z, Conway ME, et al. Enhanced task-related brain activation and resting perfusion in healthy older adults after chronic blueberry supplementation. Appl Physiol Nutr Metab. 2017;42:773-779.9. Conner TS, Brookie KL, Carr AC, et al. Let them eat fruit! The effect of fruit and vegetable consumption on psychological well-being in young adults: a randomized controlled trial. PLoS One. 2017;12:e0171206.10. Morris MC, Tangney CC, Wang Y, et al. MIND diet associated with reduced incidence of Alzheimer's disease. Alzheimers Dement. 2015;11:1007-1014.11. Wallace CJK, Milev R. The effects of probiotics on depressive symptoms in humans: a systematic review. Ann Gen Psychiatry. 2017;16:14.12. Morris MC, Tangney CC, Wang Y, et al. MIND diet slows cognitive decline with aging. Alzheimers Dement. 2015;11:1015-1022.13. Topiwala A, Allan CL, Valkanova V, et al. Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study. BMJ. 2017;357:j2353.14. Beyer JL, Payne ME. Nutrition and bipolar depression. Psychiatr Clin North Am. 2016;39:75-86. 

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