In This Issue: Volume 33, No. 3

Novel Insights Into the Causes of Schizophrenia
Groundbreaking work by a Harvard team represents a bold step in our journey toward understanding schizophrenia.

Autism, Pregnancy, and SSRIs
The author sets the record straight on the burgeoning field of reproductive psychiatry.

QTc Prolongation Associated With Psychotropics
Which lifestyle factors exacerbate the risk of QT prolongation and cardiovascular effects? That question and more addressed in this CME.

It’s Been a Long Time Coming
In one study, psychological support, social support (eg, job training), and other psychosocial interventions and medications were found to have better outcomes than those whose primary treatments focused on medication management. And that’s not the only good news. By Allan Tasman, MD

SPECIAL REPORT: PERSONALITY DISORDERS PART 2

Dialectical Behavior Therapy Skills Training
DBT is the most studied treatment available for borderline personality disorder and suicidal behavior, and it is widely recommended as a front-line treatment for these problems in professional guidelines.

The Neurobiology of Borderline Personality Disorder
To treat BPD more effectively, it helps to conceptualize the major symptoms as neuropsychiatric. They evolve from a complex interaction between environmental, anatomical, functional, genetic, and epigenetic factors.

Mentalization-Based Treatment: Borderline Personality Disorder
Mentalization lies at the root of psychological health and resilience as a common process relevant to all psychotherapies.

COMMENTARIES

Depression: A 5-Minute Seminar for Patients
We can teach patients a lot about the biopsychosocial causes of depression-even in 5 minutes. By Ronald W. Pies, MD.

Why Clozapine Use Varies by State
Reasons for the overall low rate of clozapine use brings to light questionable decisions on the part of policymakers. By E. Fuller Torrey, MD.

Incorporating Meditation Training Into an Outpatient Psychiatry Practice
Meditation training is a valuable, thoroughly secular tool for psychiatrists to incorporate into our patient practices-and our own personal self-care routines. Here: the basics.

5 Domains of Negative Symptoms of Schizophrenia
Negative symptoms identified from the Negative Symptom Assessment and the behaviors that might be observed in each of 5 domains.

The Role of Psychiatrists in HIV Prevention
Because over half of persons with HIV infection have a lifetime history of depression or bipolar disorder, psychiatrists are uniquely positioned to provide both preventive and therapeutic interventions to vulnerable patients.

Aging With Developmental Disabilities, Part 1: Fragile X–Associated Disorders
A quick guide to common neurodevelopmental conditions and their associated late-life neuropsychiatric manifestations.

POETRY OF THE TIMESThe Stethoscope
“A trillion heartbeats later, the stethoscope is no more than an ornament we drape around our necks like a prop.”

PAIN MANAGEMENTPreventing Opioid Overdose Deaths and Misuse
The involvement of a psychiatrist early in the care of patients addicted to opioids may prevent further abuse. Here's why.