First AD

Second AD

C. Delusions of parasitosis (eg, bugs crawling on or inside the skin)

On top of the symptoms in the quiz question, it should be noted that very high doses of methamphetamine will trigger some or all of the following symptoms: agitation, confusion, anxiety, irritability, dysphoria, violent behavior, impairment of psychomotor and cognitive skills, stereotypy (punding), auditory hallucinations, panic, formication (delusions of parasites or insects on the skin), and paranoia.

During the end stage of the methamphetamine binge, known as “tweaking,” euphoria is gradually replaced by negative feelings (anxiety, feeling of emptiness) and most or all of the symptoms described above. The crash phase follows and is characterized by intense fatigue, uncontrollable sleepiness, and catnapping.

Short-term physiological effects of methamphetamine and amphetamine include loss of appetite, tachycardia, hypertension, tachypnea, mydriasis, and raised body temperature. At higher doses, fever, sweating, headache, blurred vision, dizziness, stomach cramps, muscle fatigue and cramps, chest pains, shaking, dehydration, nausea, and vomiting can occur.

Neurobiology and Clinical Manifestations of Methamphetamine Neurotoxicity

Substance Use Disorder

Quizzes

What are the most common symptoms of methamphetamine abuse? Test your skills in this quiz.

Mini Quiz: Chronic Methamphetamine Use

Anna Moszczynska, PhD