New Hope for PTSD Treatment?


The latest trial results for MDMA-assisted therapy are in—and they are eye-catching.

Existing treatments for posttraumatic stress disorder (PTSD) are few in number and, too often, ineffective. Although still classified as a Schedule I drug, methylenedioxymethamphetamine (MDMA) has improved symptoms PTSD in clinical trials.

In this Mental Health Minute, Tiago Reis Marques, MD, PhD, shares the results of a new phase 3 trial, in which the MDMA-assisted arm of the study outperformed the placebo by 35%. He revisits the history of MDMA and looks to the future, when this Schedule I drug may be approved as a legal treatment.

Dr Marques is a senior clinical fellow on the Faculty of Medicine at Imperial College London, an instructor at the Institute of Psychiatry in King’s College, and the CEO of Pasithea Therapeutics.

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