A 5-Question Quiz on MDD: Round 4

December 1, 2016

Which symptom can help distinguish bipolar from unipolar depression? How does repetitive transcranial magnetic stimulation compare with ECT? Answer these questions and more.

 

Question 1:

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The correct answer is A. The relapse rate, although high, is lower than for non-psychotherapeutic treatments.

Source: Steinert C, Hofmann M, Kruse J, Leichsenring F. Relapse rates after psychotherapy for depression-stable long-term effects? A meta-analysis. J Affect Disord. 2014;168:107-118.

 

Question 2.

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The correct answer is C. Psychomotor speed

Source: Rosenblat JD, Kakar R, McIntyre RS. The cognitive effects of antidepressants in major depressive disorder: a systematic review and meta-analysis of randomized clinical trials. Int J Neuropsychopharmacol. 2015;19(2).

 

Question 3.

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The correct answer is C. Is less effective for psychotic depression

Source: Ren J, Li H, Palaniyappan L, et al. Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: a systematic review and meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry. 2014;51:181-189.

 

Question 4.

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The correct answer is D. Ketamine

Source: Kishimoto T, Chawla JM, Hagi K, et al. Single-dose infusion ketamine and non-ketamine N-methyl-d-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories. Psychol Med. 2016;46:1459-1472.

 

Question 5.

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The correct answer is E. Hypersomnia

Source: Hirschfeld RM. Differential diagnosis of bipolar disorder and major depressive disorder. J Affect Disord. 2014;169(suppl 1):S12-S16.