Substance-Induced Psychosis and Conversion to Schizophrenia

Up to 50% of cases of cannabis-induced psychosis covert to schizophrenia. A new study provides striking evidence for abuse of other substances and schizophrenia onset.

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Comorbidity
• One hypothesis for the comorbidity between psychiatric disorders and substance use disorders is that patients use substances as a means to “self-medicate”
• However, cannabis use may accelerate the onset of schizophrenia in vulnerable individuals in a dose-dependent manner [1]

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