Brian Miller, MD, PhD, MPH

Exploring the prevalence and implications of psychotropic polypharmacy in patients taking clozapine with treatment-resistant schizophrenia.

Nearly half of catatonia patients relapse within two years, highlighting the need for effective long-term management strategies and potential benefits of antipsychotics.

Adjunctive rTMS for antidepressant nonresponders? Researchers performed a randomized comparison with current antidepressant treatment approaches.

Baseline clinical factors and early improvement in overall and specific depressive symptoms predict response to rTMS in patients with depression.

Novel treatment for cocaine use disorder? Researchers performed a randomized, double-blind, placebo-controlled trial of lorcaserin.

Does reduced blood monitoring impact the detection of hematological abnormalities in clozapine-treated patients? Researchers performed a chart review study from the COVID-10 pandemic.

Will this help my sleep and mood? Researchers investigated the effects of noninvasive neurostimulation on sleep quality and depressive symptoms in patients with major depressive disorder in a meta-analysis of randomized controlled trials.

Sleep and suicide? Researchers investigated improvement in insomnia as a pathway underlying the antisuicidal properties of clozapine.

Will this procedure help? Researchers investigated early symptom improvement and other clinical predictors of response to repetitive transcranial magnetic stimulation for depression.

The weight-adjusted waist index was a stronger predictor of depressive symptoms than either body mass index or waist circumference.

What is their comparative safety?

Do physical health conditions in childhood affect ADHD symptoms at age 17 years? Researchers investigated these associations in a large cohort study.

What are the risks and benefits of antipsychotic polypharmacy for the treatment of schizophrenia?

A more useful measure than BMI or waist circumference? Researchers analyzed the association between weight-adjusted waist index and depressive symptoms.

Gone in a puff of smoke? Researchers investigated the effectiveness of antipsychotics in reducing the risk of hospitalization in patients with first-episode psychosis and co-occurring CUD.

Compared with divided dosing, patients with once-daily dosing had shorter illness duration and better clinical outcomes.

“The heart of the matter.” Researchers investigated the risk of cardiovascular disease associated with long-term ADHD medication use.

More than a gut feeling? Researchers investigated associations between the gut microbiome and treatment resistance in schizophrenia.

“Can I use this at home?” Researchers performed a randomized clinical trial of home-use transcranial direct current stimulation in patients with depression.

“Listen to your heart.” Researchers investigated the risks of cardiometabolic disease, heart failure, and mortality in bipolar disorder in a population-based cohort study.

“I wish I were dead.” Researchers performed a meta-analysis of psychological pain and suicidality in patients with depression.

“Weight” a minute! Researchers investigated the impact of body mass index on the clinical features of bipolar disorder in the STEP-BD study.

To divide or not to divide? Researchers compared clinical features, side effects, and blood levels between once daily versus divided clozapine dosing regimens.

Will this medication make me gain weight? Researchers analyzed response to antidepressant treatment as a predictor of incident metabolic syndrome in a cohort of patients with depression.

What are the cardiometabolic risks of polypharmacy with quetiapine and long-acting injectable paliperidone in patients with schizophrenia?

Researchers performed a systematic review and meta-analysis of the effects of clozapine on cognitive function in patients with treatment-resistant schizophrenia.

Researchers performed a double-blind, placebo-controlled pilot study of solriamfetol.

Ketamine for anxiety? Researchers performed a systematic review and meta-analysis of ketamine’s anxiolytic effects.

Young men appear to be particularly susceptible to the effects of cannabis on schizophrenia.