Tardive dyskinesia, an involuntary athetoid or choreiform movements, generally of the tongue, lower face and jaw, and extremities, is highly prevalent in patients with schizophrenia after long-term antipsychotic use. What about clozapine for TD?
Why D2 blockade alone falls short in schizophrenia, and what neurotransmitter, genetic and neuroimaging research means for treatment-resistant patients.
New automated connectomics maps synapses across circuits, revealing how inhibitory neuron subtypes shape decision-making and may explain circuit dysfunction in psychiatric disorders.