David N. Osser, MD

There appears to be some confusion regarding the efficacy of aripiprazole in bipolar mania and depression and for preventing bipolar episodes.

An international task force of experts in the diagnosis and treatment of bipolar disorder was recently convened to address concerns about DSM-5 criteria, particularly the definitions of manic episodes. The DSM’s duration criteria is an area of concern.

Current estimates are that 4% to 5% of the population is at risk for a disorder on the bipolar spectrum. Among the patients of that spectrum are those with a disturbance of temperament in the direction of hypomania.

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