Author | David N. Osser, MD


The Case Against Antidepressants for Bipolar Depression: Findings from STEP-BD

June 30, 2020


Do you prescribe antidepressants for your patients with bipolar depression? If so, think again, and consider results from these studies.

Cannabis: Patients With Bipolar Should Avoid Use

April 01, 2020


Regardless of whatever short-term benefit patients perceive from cannabis, the evidence points clearly to an association between usage and worsening course of bipolar disorder over time.

The Neuroprotective Effects of Lithium

February 14, 2020


Do you need help persuading patients to try lithium?

Clinical Updates From Bipolar Telehealth

December 31, 2019


There appears to be some confusion regarding the efficacy of aripiprazole in bipolar mania and depression and for preventing bipolar episodes.

Lamotrigine: Its Role in Bipolar Disorder

November 26, 2019


The good, the bad, and the efficacy of lamotrigine.

Mania and Hypomania: The Latest Thinking on Duration of Episodes and Other Features

October 29, 2019


An international task force of experts in the diagnosis and treatment of bipolar disorder was recently convened to address concerns about DSM-5 criteria, particularly the definitions of manic episodes. The DSM’s duration criteria is an area of concern.

Fasten Your Seatbelts

September 25, 2019


The evidence is clear: bipolar disorder is frequently both underdiagnosed and overdiagnosed.

Hyperthymic Temperament

September 13, 2019


Current estimates are that 4% to 5% of the population is at risk for a disorder on the bipolar spectrum. Among the patients of that spectrum are those with a disturbance of temperament in the direction of hypomania.

Sorting Out the Antidepressant “Withdrawal” Controversy

March 11, 2019


With a combined 70+ years of clinical experience, the authors discuss scenarios that represent two possible outcomes of discontinuing serotonergic antidepressants.

New Psychopharmacology Algorithms

August 05, 2015


Dr David Osser offers compelling reasons why you might want to take a look at these 7 algorithms, each of which offers actionable consultations-usually in under 2 minutes.