Rajnish Mago, MD




Lamotrigine for Major Depressive Disorder Is Inappropriate

April 12, 2013

Lamotrigine is an important option in bipolar disorders. However, many clinicians also use it in patients with a (unipolar) depressive disorder who have not responded adequately to conventional antidepressants.

Bupropion After Nonresponse or Partial Response to an SSRI or SNRI?

March 02, 2012

While SSRIs and SNRIs are valuable in the treatment of major depression, partial response or nonresponse occurs in many patients. Research has found that bupropion was the most frequently chosen agent for addition to an SSRI after inadequate response.

Efficacy of Drugs in Bipolar Depression: What the Data Show

May 12, 2010

This is the second installment of a new series in which clinically relevant research is briefly discussed and, perhaps more important, a few tips on how to read and interpret research studies are presented. Your feedback, suggestions, and questions are eagerly solicited at rajnish.mago@jefferson.edu.

Sleep Hygiene

December 11, 2009

Simple but powerful suggestions to get a better night's sleep.

Practical Implications of a Study on Treating Chronic Insomnia

December 01, 2009

More than a thousand articles on mental disorders are published in medical journals each month! Also, clinicians have limited training, time, and inclination to keep up with reading research articles critically on a regular basis. Thus, a disturbing disconnect (for which there are no easy solutions) exists between clinical research and usual clinical practice.

Coffee, Cigarettes and Meds: What Are the Metabolic Effects?

May 01, 2005

Heavy smoking and caffeine intake are highly prevalent in patients with psychiatric disorders, both of which significantly impact the metabolism of a number of psychotropic medications. Hence, these factors should be routinely considered in making prescribing decisions.